Meaningful Change in Depression Symptoms Assessed with the Patient Health Questionnaire (PHQ-9) and Montgomery-Åsberg Depression Rating Scale (MADRS) Among Patients with Treatment Resistant Depression in Two, Randomized, Double-blind, Active-controlled Trials of Esketamine Nasal Spray Combined With a New Oral Antidepressant.

Background: Patients with major depressive disorder who do not respond to ≥2 different pharmacological treatments within the current depressive episode are considered to have treatment resistant depression (TRD). This analysis determined meaningful change thresholds (MCT) of the Patient Health Quest...

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Publicado en:Journal of Affective Disorders Vol. 281; pp. 767 - 776
Autores principales: Hudgens, Stacie, Floden, Lysbeth, Blackowicz, Michael, Jamieson, Carol, Popova, Vanina, Fedgchin, Maggie, Drevets, Wayne C., Cooper, Kimberly, Lane, Rosanne, Singh, Jaskaran
Formato: research tables/charts Journal Article
Publicado: Elsevier B.V. Feb2021
Acceso en línea:Ver este registro en EBSCOhost