Green Synthesis of Magnetic Nanoparticles Using Satureja hortensis Essential Oil toward Superior Antibacterial/Fungal and Anticancer Performance.

The biological synthesis of nanoparticles, due to their environmental and biomedical properties, has been of particular interest to scientists and physicians. Here, iron nanoparticles (FeNPs) were synthesized using Satureja hortensis essential oil. Then, the chemical, functional, and morphological p...

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Publicado en:BioMed Research International pp. 1 - 15
Autores principales: Ahmadi, Shahram, Fazilati, Mohammad, Nazem, Habibollah, Mousavi, Seyyed Mojtaba
Formato: pictorial research tables/charts Journal Article
Publicado: Wiley-Blackwell 1/20/2021
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 1/20/2021
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        148206034
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        10.1155/2021/8822645
        148206034
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        atl: Green Synthesis of Magnetic Nanoparticles Using Satureja hortensis Essential Oil toward Superior Antibacterial/Fungal and Anticancer Performance.
      aug:
        au:
          Ahmadi, Shahram
          Fazilati, Mohammad
          Nazem, Habibollah
          Mousavi, Seyyed Mojtaba
        affil: Department of Science, Payame Noor University (PNU), Tehran, Iran
      sug:
        subj:
          Nanoparticles
          Plant Extracts Pharmacodynamics
          Plants, Medicinal Pharmacodynamics
          Essential Oils
          Bacterial Infections
          Antibiotics
          Antiinfective Agents
          Antineoplastic Agents
          Human
          Cell Line, Tumor Drug Effects
          Staphylococcus Aureus
          Gram-Positive Bacteria
          Pseudomonas Infections
          Escherichia Coli Infections
          Candida Albicans
      ab: The biological synthesis of nanoparticles, due to their environmental and biomedical properties, has been of particular interest to scientists and physicians. Here, iron nanoparticles (FeNPs) were synthesized using Satureja hortensis essential oil. Then, the chemical, functional, and morphological properties of these nanoparticles were characterized by typical experiments such as Uv-Vis, FTIR, XRD, FE-SEM, PSA, zeta potential, EDX, and EDX mapping. The results indicated Fe nanoparticles' formation with a cubic morphological structure and a particle size in the range of 9.3-27 nm. The antimicrobial effects of these nanoparticles were further evaluated using disc diffusion, minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC), and minimum fungal concentration (MFC) against two gram-positive bacterial strains (Staphylococcus aureus and Corynebacterium glutamicum), two gram-negative bacterial strains (Pseudomonas aeruginosa and Escherichia coli), and one fungus species Candida albicans. The results showed that green-synthesized Fe nanoparticles possessed higher antimicrobial properties than Satureja hortensis essential oil against selected pathogenic microorganisms, especially Gram-negative bacteria. Finally, the anticancer effect of these Fe nanoparticles was investigated on human cancer cells, K-562, and MCF-7, by the MTT assay. The results showed the anticancer effect of these nanoparticles against selected cell lines.
      pubtype: Academic Journal
      doctype:
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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