A Case of Cutaneous Leishmaniasis Responding to Systemic Liposomal Amphotericin B Treatment.
Leishmania is a vector-induced endemic tropical disease caused by protozoans. The most common cutaneous, mucosal and visceral forms are the cutaneous form. The main drugs in treatment are pentavalent antimony compounds, but their side effects create limitation of use. Local antimony compounds are us...
| Publicado en: | Journal of Pediatric Infection / Çocuk Enfeksiyon Dergisi Vol. 14; no. 4; pp. 229 - 233 |
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| Autores principales: | , , , , , , , |
| Formato: | case study pictorial Journal Article |
| Publicado: |
Journal of Pediatric Infection / Cocuk Enfeksiyon Dergisi
ara2020
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=148215138&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 148215138 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 13071068 87WO jtl: Journal of Pediatric Infection / Çocuk Enfeksiyon Dergisi issn: 13071068 maglogo: N pubinfo: dt: ara2020 vid: 14 iid: 4 pid: 50187 pub: Journal of Pediatric Infection / Cocuk Enfeksiyon Dergisi artinfo: ui: 148215138 148215138 148215138 10.5578/ced.202069 148215138 ppf: 229 ppct: 4 formats: fmt: @attributes: type: P tig: atl: A Case of Cutaneous Leishmaniasis Responding to Systemic Liposomal Amphotericin B Treatment. aug: au: Taşkın, Esra Çakmak Kütükçü, Hatice Büşra Konca, Hatice Kübra Arga, Gül Özdemir, Halil Akay, Bengü Nisa Çiftçi, Ergin İnce, Erdal affil: Division of Pediatric Infectious Diseases, Department of Pediatrics, Ankara University School of Medicine, Ankara, Turkey. sug: subj: Leishmaniasis Drug Therapy Amphotericin B Therapeutic Use Male Infant Skin Diseases, Parasitic Amphotericin B Administration and Dosage Infant: 1-23 months Male ab: Leishmania is a vector-induced endemic tropical disease caused by protozoans. The most common cutaneous, mucosal and visceral forms are the cutaneous form. The main drugs in treatment are pentavalent antimony compounds, but their side effects create limitation of use. Local antimony compounds are used primarily in the treatment of cutaneous leishmaniasis. In some cases, alternative treatment modalities are required due to insufficient response to local treatment. Systemic amphotericin B treatment is one of the alternative treatments. In a patient who developed cutaneous Leishmania at 21 months and who did not respond with local meglumine antimoniate therapy, a total of 21 mg/kg dose of systemic amphotericin B was given intermittently and successful results were obtained. Leishmania, protozoonların neden olduğu, vektör kaynaklı endemik bir tropikal hastalıktır. Kutanöz, mukozal ve visseral formları içinde en sık görüleni kutanöz formdur. Tedavide esas ilaç pentavalan antimon bileşiklerdir, ancak yan etkileri kullanım kısıtlılığı yaratmaktadır. Kutanöz Leishmania tedavisinde öncelikle lokal antimon bileşikleri kullanılır. Bazı vakalarda lokal tedaviye yanıtın yetersiz olması nedeniyle alternatif tedavi uygulamaları gerekir. Sistemik amfoterisin B tedavisi alternatif tedavilerden biridir. Bizde 21 aylık yüzde kutanöz Leishmania gelişen ve lokal meglumin antimonat tedavisi ile yanıt alınamayan bir hastada toplam 21 mg/kg dozda sistemik amfoterisin B aralıklı verilerek başarılı sonuç elde edilmiştir. pubtype: Academic Journal doctype: case study pictorial Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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