Different types of bullae of limbs with necrotizing fasciitis predict different outcome: a prospective study.
Study objective: Necrotizing fasciitis (NF) is an uncommon life-threatening necrotizing skin and soft tissue infection. Bullae are special skin manifestations of NF. This study was conducted to analyze the differences between different types of bullae of limbs with NF for providing the information t...
| Publicado en: | Infection Vol. 49; no. 1; pp. 135 - 145 |
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| Autores principales: | , , , , , , , , , , |
| Formato: | pictorial research tables/charts Journal Article |
| Publicado: |
Springer Nature
2021
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=148427265&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 148427265 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 03008126 NXO jtl: Infection issn: 03008126 maglogo: N pubinfo: dt: 2021 vid: 49 iid: 1 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 148427265 147895907 148427265 148427265 10.1007/s15010-020-01559-5 148427265 ppf: 135 ppct: 10 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Different types of bullae of limbs with necrotizing fasciitis predict different outcome: a prospective study. aug: au: Huang, Tsung-Yu Tsai, Yao-Hung Kuo, Liang-Tseng Hsu, Wei-Hsiu Hsiao, Cheng-Ting Hung, Chien-Hui Huang, Wan-Yu Wu, Han-Ru Chuang, Hui-Ju Li, Yen-Yao Peng, Kuo-Ti affil: Division of Infectious Diseases, Department of Internal Medicine, Chang Gung Memorial Hospital, Chiayi, Taiwan sug: subj: Blister Extremities Physiopathology Fasciitis, Necrotizing Therapy Bacteremia Human Comparative Studies Prospective Studies Vibrio Infections ab: Study objective: Necrotizing fasciitis (NF) is an uncommon life-threatening necrotizing skin and soft tissue infection. Bullae are special skin manifestations of NF. This study was conducted to analyze the differences between different types of bullae of limbs with NF for providing the information to emergency treatment. Methods: From April 2015 to August 2018, patients were initially enrolled based on surgical confirmation of limbs with NF. According to the presence of different bullae types, patients were divided into no bullae group (Group N), serous-filled bullae group (Group S), and hemorrhagic bullae group (Group H). Data such as demographics, clinical outcomes, microbiological results, presenting symptoms/signs, and laboratory findings were compared among these groups. Results: In total, 187 patients were collected, with 111 (59.4%) patients in Group N, 35 (18.7%) in Group S, and 41 (21.9%) in Group H. Group H had the highest incidence of amputation, required intensive care unit care, and most patients infected with Vibrio species. In Group N, more patients were infected with Staphylococcus spp. than Group H. In Group S, more patients were infected with β-hemolytic Streptococcus than Group H. Patients with bacteremia, shock, skin necrosis, anemia, and longer prothrombin time constituted higher proportions in Group H and S than in Group N. Conclusions: In southern Taiwan, patients with NF accompanied by hemorrhagic bullae appear to have more bacteremia, Vibrio infection, septic shock, and risk for amputation. If the physicians at the emergency department can detect for the early signs of NF as soon as possible, and more patient's life and limbs may be saved. pubtype: Academic Journal doctype: pictorial research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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