Effect of polydextrose-containing beverage on bowel habits and gastrointestinal symptoms of constipated subjects: a pilot study.
Introduction: Indonesians have a low intake of dietary fibre, a key component for an increased incidence in constipation. Available data have documented the benefits of polydextrose (PDX) in healthy subjects. However, data on constipated subjects are lacking. This study aimed to investigate the effe...
| Publicado en: | Malaysian Journal of Nutrition Vol. 26; no. 3; pp. 353 - 368 |
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| Autores principales: | , , , , |
| Formato: | research tables/charts randomized controlled trial Journal Article |
| Publicado: |
Nutrition Society of Malaysia
Dec2020
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=148446179&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 148446179 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 1394035X 6CKY jtl: Malaysian Journal of Nutrition issn: 1394035X maglogo: N pubinfo: dt: Dec2020 vid: 26 iid: 3 pid: 49148 pub: Nutrition Society of Malaysia artinfo: ui: 148446179 148446179 148446179 10.31246/mjn-2019-0052 148446179 ppf: 353 ppct: 15 formats: fmt: @attributes: type: P tig: atl: Effect of polydextrose-containing beverage on bowel habits and gastrointestinal symptoms of constipated subjects: a pilot study. aug: au: Kurniawan, Mohamad Yulianto Istiftiani, Nourmatania Heryati, Lilis Reinaldo, Christian Susanto, Fendy affil: Department of Scientific and Regulatory Affairs, PT. Amerta Indah Otsuka, Jakarta, Indonesia sug: subj: Beverages Prebiotics Therapeutic Use Polysaccharides Administration and Dosage Constipation Prevention and Control Defecation Signs and Symptoms, Digestive Prevention and Control Treatment Outcomes Human Indonesia Randomized Controlled Trials Random Assignment Feces Abdominal Pain Prevention and Control Flatulence Prevention and Control Bloat Prevention and Control Dietary Fiber Gut Microbiota ab: Introduction: Indonesians have a low intake of dietary fibre, a key component for an increased incidence in constipation. Available data have documented the benefits of polydextrose (PDX) in healthy subjects. However, data on constipated subjects are lacking. This study aimed to investigate the effect of consuming a PDX (prebiotic) beverage on bowel habits and gastrointestinal symptoms of constipated subjects over seven days. Methods: This was a randomised, non-blinded, nonplacebo- controlled parallel design study involving 24 subjects, divided equally into two groups. Group A (active control group) consisted of 12 subjects, consuming one serving size of 6g PDX beverage. While Group B (intervention group) consisted of 12 subjects, consuming two servings of the same product, containing 12g PDX beverage. Changes in bowel habits (constipation score, stool frequency and stool consistency) and gastrointestinal symptoms (abdominal pain, bloating and flatulence) were monitored. Results: Within seven days, Group B showed 4.9% more reduction in overall constipation mean score than that of Group A. Positive improvement in gastrointestinal symptoms were reported: i.e. abdominal pain (M = -0.08±0.43), bloating (M = -0.29±0.37) and flatulence (M = -0.17±0.47). Majority of subjects had desirable stool frequency (87.5%, >3 defecations/week) and stool consistency (58.3%, type 4). These improvements were due to the fact that PDX provides physiological effects consistent with prebiotic fibre, which alters the gut microbiota composition during the fermentation cycle in the large intestine. Conclusion: Findings of this study suggested that daily PDX beverage consumption effectively improved bowel habits, with fewer constipated subjects reporting of gastrointestinal symptoms. pubtype: Academic Journal doctype: research tables/charts randomized controlled trial Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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