Radiomics of hepatocellular carcinoma.

The diagnosis of hepatocellular carcinoma relies largely on non-invasive imaging, and is well suited for radiomics analysis. Radiomics is an emerging method for quantification of tumor heterogeneity by mathematically analyzing the spatial distribution and relationships of gray levels in medical imag...

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Publicado en:Abdominal Radiology Vol. 46; no. 1; pp. 111 - 124
Autores principales: Lewis, Sara, Hectors, Stefanie, Taouli, Bachir
Formato: Journal Article
Publicado: Springer Nature 2021
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Springer Nature
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        atl: Radiomics of hepatocellular carcinoma.
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          Lewis, Sara
          Hectors, Stefanie
          Taouli, Bachir
        affil: BioMedical Engineering and Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA
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      ab: The diagnosis of hepatocellular carcinoma relies largely on non-invasive imaging, and is well suited for radiomics analysis. Radiomics is an emerging method for quantification of tumor heterogeneity by mathematically analyzing the spatial distribution and relationships of gray levels in medical images. The published studies on radiomics analysis of HCC provide encouraging data demonstrating potential utility for prediction of tumor biology, molecular profiles, post-therapy response, and outcome. The combination of radiomics data and clinical/laboratory information provides added value in many studies. Radiomics is a multi-step process that requires optimization and standardization, the development of semi-automated or automated segmentation methods, robust data quality control, and refinement of algorithms and modeling approaches for high-throughput data analysis. While radiomics remains largely in the research setting, the strong associations of predictive models and nomograms with certain pathologic, molecular, and immune markers with tumor aggressiveness and patient outcomes, provide great potential for clinical applications to inform optimized treatment strategies and patient prognosis.
      pubtype: Academic Journal
      doctype: Journal Article
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    language: English
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