Carcinoma of unknown primary with hepatic metastases: a need of judicious and contemplative diagnostic algorithm.

Carcinoma of Unknown Primary presenting primarily as hepatic metastases encompasses a dismal subgroup of tumors with a median survival of 5.9 months. Adenocarcinoma is the most common histological subtype identified upon biopsy and the primary tumor remains undetectable in the majority of cases desp...

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Detalles Bibliográficos
Publicado en:Abdominal Radiology Vol. 46; no. 1; pp. 257 - 268
Autores principales: Shivaji, Vikram Sai, Wilson, Joseph Charles, Schmidt, Noemi L., Kolokythas, Orpheus, Lalwani, Neeraj
Formato: Journal Article
Publicado: Springer Nature 2021
Acceso en línea:Ver este registro en EBSCOhost
Descripción
Sumario:Carcinoma of Unknown Primary presenting primarily as hepatic metastases encompasses a dismal subgroup of tumors with a median survival of 5.9 months. Adenocarcinoma is the most common histological subtype identified upon biopsy and the primary tumor remains undetectable in the majority of cases despite extensive workup. It is important to have a validated and standardized algorithm to follow these tumors to avoid unnecessary tests, as the wishes and health status of the patient represent the principal concerns. The purpose of this paper is to briefly review the current literature on carcinoma of unknown primary with hepatic metastases and propose a standardized diagnostic approach.