Recent Advances in Predicting Protein S-Nitrosylation Sites.

Protein S-nitrosylation (SNO) is a process of covalent modification of nitric oxide (NO) and its derivatives and cysteine residues. SNO plays an essential role in reversible posttranslational modifications of proteins. The accurate prediction of SNO sites is crucial in revealing a certain biological...

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Publicado en:BioMed Research International pp. 1 - 11
Autores principales: Zhao, Qian, Ma, Jiaqi, Xie, Fang, Wang, Yu, Zhang, Yu, Li, Hui, Sun, Yuan, Wang, Liqi, Guo, Mian, Han, Ke
Formato: review tables/charts Journal Article
Publicado: Wiley-Blackwell 2/11/2021
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Wiley-Blackwell
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        10.1155/2021/5542224
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        atl: Recent Advances in Predicting Protein S-Nitrosylation Sites.
      aug:
        au:
          Zhao, Qian
          Ma, Jiaqi
          Xie, Fang
          Wang, Yu
          Zhang, Yu
          Li, Hui
          Sun, Yuan
          Wang, Liqi
          Guo, Mian
          Han, Ke
        affil: School of Computer and Information Engineering, Heilongjiang Provincial Key Laboratory of Electronic Commerce and Information Processing, Harbin University of Commerce, Harbin 150028, China
      sug:
        subj:
          Proteins
          Nitric Oxide Metabolism
          Drug Design
          Cysteine Metabolism
          Bioinformatics
      ab: Protein S-nitrosylation (SNO) is a process of covalent modification of nitric oxide (NO) and its derivatives and cysteine residues. SNO plays an essential role in reversible posttranslational modifications of proteins. The accurate prediction of SNO sites is crucial in revealing a certain biological mechanism of NO regulation and related drug development. Identification of the sites of SNO in proteins is currently a very hot topic. In this review, we briefly summarize recent advances in computationally identifying SNO sites. The challenges and future perspectives for identifying SNO sites are also discussed. We anticipate that this review will provide insights into research on SNO site prediction.
      pubtype: Academic Journal
      doctype:
        review
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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