Higher temporal resolution multiband fMRI provides improved presurgical language maps.
Purpose: We investigated the hypothesis that increasing fMRI temporal resolution using a multiband (MB) gradient echo-echo planar imaging (GRE-EPI) pulse sequence provides fMRI language maps of higher statistical quality than those acquired with a traditional GRE-EPI sequence. Methods: This prospect...
| Publicado en: | Neuroradiology Vol. 63; no. 3; pp. 439 - 446 |
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| Autores principales: | , , , , , , , , , , |
| Formato: | diagnostic images research tables/charts Journal Article |
| Publicado: |
Springer Nature
Mar2021
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=148678448&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 148678448 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00283940 NYZ jtl: Neuroradiology issn: 00283940 maglogo: N pubinfo: dt: Mar2021 vid: 63 iid: 3 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 148678448 146294488 148678448 148678448 10.1007/s00234-020-02569-8 148678448 ppf: 439 ppct: 7 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Higher temporal resolution multiband fMRI provides improved presurgical language maps. aug: au: Mark, Ian T. Black, David F. DeLone, David R. Passe, Theodore J. Witte, Robert J. Little, Jason T. Ho, Mai-Lan Fagan, Andrew J. Parney, Ian F. Burns, Terence C. Welker, Kirk M. affil: Department of Radiology, Mayo Clinic, 200 1st St. SW, 55905, Rochester, MN, USA sug: subj: Magnetic Resonance Imaging Language Temporal Lobe Physiology Human Prospective Studies Paired T-Tests ab: Purpose: We investigated the hypothesis that increasing fMRI temporal resolution using a multiband (MB) gradient echo-echo planar imaging (GRE-EPI) pulse sequence provides fMRI language maps of higher statistical quality than those acquired with a traditional GRE-EPI sequence. Methods: This prospective study enrolled 29 consecutive patients receiving language fMRI prior to a potential brain resection for tumor, AVM, or epilepsy. A 4-min rhyming task was performed at 3.0 Tesla with a traditional GRE-EPI pulse sequence (TR = 2000, TE = 30, matrix = 64/100%, slice = 4/0, FOV = 24, slices = 30, time points = 120) and an additional MB GRE-EPI pulse sequence with an acceleration factor of 6 (TR = 333, TE = 30, matrix 64/100%, slice = 4/0, FOV = 24, time points = 720). Spatially filtered t statistical maps were generated. Volumes of interest (VOIs) were drawn around activations at Broca's, dorsolateral prefrontal cortex, Wernicke's, and the visual word form areas. The t value maxima were measured for the overall brain and each of the VOIs. A paired t test was performed for the corresponding traditional and MB GRE-EPI measurements. Results: The mean age of subjects was 42.6 years old (18–75). Sixty-two percent were male. The average overall brain t statistic maxima for the MB pulse sequence (t = 15.4) was higher than for the traditional pulse sequence (t = 9.3, p = <.0001). This also held true for Broca's area (p < 0.0001), Wernicke's area (p <.0001), dorsolateral prefrontal cortex (p <.0001), and the visual word form area (p <.0001). Conclusion: A MB GRE-EPI fMRI pulse sequence employing high temporal resolution provides clinical fMRI language maps of greater statistical significance than those obtained with a traditional GRE-EPI sequence. pubtype: Academic Journal doctype: diagnostic images research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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