Detection of Fusion Genes to Determine Minimal Residual Disease in Leukemia Using Next-Generation Sequencing.

BACKGROUND: Measuring minimal residual disease (MRD), the persistence of leukemic cells after treatment, is important for monitoring leukemia recurrence. The current methods for monitoring MRD are flow cytometry, to assess aberrant immune phenotypes, and digital droplet PCR (ddPCR), to target geneti...

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Bibliographic Details

Published in:	Clinical Chemistry Vol. 66; no. 8; pp. 1084 - 1093
Main Authors:	de Boer, Eddy N., Johansson, Lennart F., Lange, Kim de, Bosga-Brouwer, Anneke G., den Berg, Eva van, Sikkema-Raddatz, Birgit, van Diemen, Cleo C.
Format:	Journal Article
Published:	Oxford University Press / USA Aug2020
Online Access:	View this record in EBSCOhost