Generalized linear mixed-model (GLMM) trees: A flexible decision-tree method for multilevel and longitudinal data.

Objective: Decision-tree methods are machine-learning methods which provide results that are relatively easy to interpret and apply by human decision makers. The resulting decision trees show how baseline patient characteristics can be combined to predict treatment outcomes for individual patients,...

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Publicado en:Psychotherapy Research Vol. 31; no. 3; pp. 313 - 326
Autores principales: Fokkema, Marjolein, Edbrooke-Childs, Julian, Wolpert, Miranda
Formato: Artículo
Publicado: Taylor & Francis Ltd Mar2021
Materias:
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Mar2021
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      pub: Taylor & Francis Ltd
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        10.1080/10503307.2020.1785037
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        atl: Generalized linear mixed-model (GLMM) trees: A flexible decision-tree method for multilevel and longitudinal data.
      aug:
        au:
          Fokkema, Marjolein
          Edbrooke-Childs, Julian
          Wolpert, Miranda
        affil:
          Department of Methods & Statistics, Institute of Psychology, Leiden University, Leiden, The Netherlands
          Evidence Based Practice Unit, Anna Freud Centre/UCL, London, UK
      su:
        United Kingdom
        Longitudinal method
        Random forest algorithms
        Decision trees
        Trees
        Treatment effectiveness
      sug:
        subj:
          United Kingdom
          Flower, Nursery Stock, and Florists' Supplies Merchant Wholesalers
          Longitudinal method
          Random forest algorithms
          Decision trees
          Trees
          Treatment effectiveness
      keyword:
        decision making
        decision-tree methods
        mixed-effects models
        multilevel data
        subgroup detection
        decision making
        decision-tree methods
        mixed-effects models
        multilevel data
        subgroup detection
      ab: Objective: Decision-tree methods are machine-learning methods which provide results that are relatively easy to interpret and apply by human decision makers. The resulting decision trees show how baseline patient characteristics can be combined to predict treatment outcomes for individual patients, for example. This paper introduces GLMM trees, a decision-tree method for multilevel and longitudinal data. Method: To illustrate, we apply GLMM trees to a dataset of 3,256 young people (mean age 11.33, 48% girls) receiving treatment at one of several mental-health service providers in the UK. Two treatment outcomes (mental-health difficulties scores corrected for baseline) were regressed on 18 demographic, case and severity characteristics at baseline. We compared the performance of GLMM trees with that of traditional GLMMs and random forests. Results: GLMM trees yielded modest predictive accuracy, with cross-validated multiple R values of.18 and.25. Predictive accuracy did not differ significantly from that of traditional GLMMs and random forests, while GLMM trees required evaluation of a lower number of variables. Conclusion: GLMM trees provide a useful data-analytic tool for clinical prediction problems. The supplemental material provides a tutorial for replicating the GLMM tree analyses in R.
      pubtype: Academic Journal
      doctype: Article
      src: R
    language: English
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