Generation of Brain Dual-Energy CT from Single-Energy CT Using Deep Learning.

Deep learning (DL) has shown great potential in conversions between various imaging modalities. Similarly, DL can be applied to synthesize a high-kV computed tomography (CT) image from its corresponding low-kV CT image. This indicates the feasibility of obtaining dual-energy CT (DECT) images without...

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Publicado en:Journal of Digital Imaging Vol. 34; no. 1; pp. 149 - 162
Autores principales: Liu, Chi-Kuang, Liu, Chih-Chieh, Yang, Cheng-Hsun, Huang, Hsuan-Ming
Formato: diagnostic images pictorial research tables/charts Journal Article
Publicado: Springer Nature Feb2021
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Feb2021
      vid: 34
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s10278-020-00414-1
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        atl: Generation of Brain Dual-Energy CT from Single-Energy CT Using Deep Learning.
      aug:
        au:
          Liu, Chi-Kuang
          Liu, Chih-Chieh
          Yang, Cheng-Hsun
          Huang, Hsuan-Ming
        affil: Department of Medical Imaging, Changhua Christian Hospital, 135 Nanxiao St, 500, Changhua County, Taiwan
      sug:
        subj:
          Brain Radiation Effects
          Deep Learning
          Brain Mapping Methods
          Radiation Dosage
          Tomography, X-Ray Computed Methods
          Human
          Image Processing, Computer Assisted Methods
          Neural Networks (Computer)
          Sensitivity and Specificity
          Spatial Behavior
          Descriptive Statistics
          Noise
      ab: Deep learning (DL) has shown great potential in conversions between various imaging modalities. Similarly, DL can be applied to synthesize a high-kV computed tomography (CT) image from its corresponding low-kV CT image. This indicates the feasibility of obtaining dual-energy CT (DECT) images without purchasing a DECT scanner. In this study, we investigated whether a low-to-high kV mapping was better than a high-to-low kV mapping. We used a U-Net model to perform conversions between different kV CT images. Moreover, we proposed a double U-Net model to improve the quality of original single-energy CT images. Ninety-eight patients who underwent brain DECT scans were used to train, validate, and test the proposed DL-based model. The results showed that the low-to-high kV conversion was better than the high-to-low kV conversion. In addition, the DL-based DECT images had better signal-to-noise ratios (SNRs) than the true (original) DECT images, but at the expense of a slight loss in spatial resolution. The mean CT number differences between the true and DL-based DECT images were within ± 1 HU. No statistically significant difference in CT number measurements was found between the true and DL-based DECT images (p > 0.05). The DL-based DECT images with improved SNR could produce low-noise virtual monoenergetic images. Our preliminary results indicate that DL has the potential to generate brain DECT images using single-energy brain CT images.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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