Implementation science research for the scale-up of evidence-based interventions for sickle cell disease in africa: a commentary.

Background: The burden of sickle cell disease (SCD) is greatest among African nations. Effective scalability of evidence-based interventions (e.g., newborn screening, health education, prophylaxis for infection, optimal nutrition and hydration, hydroxyurea therapy, blood transfusions, and transcrani...

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Publicado en:Globalization & Health Vol. 17; no. 1; pp. 1 - 5
Autores principales: Gyamfi, Joyce, Ojo, Temitope, Iwelunmor, Juliet, Ogedegbe, Gbenga, Ryan, Nessa, Diawara, Amy, Nnodu, Obiageli, Wonkam, Ambroise, Royal, Charmaine, Peprah, Emmanuel
Formato: Journal Article
Publicado: BioMed Central 2/17/2021
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Implementation science research for the scale-up of evidence-based interventions for sickle cell disease in africa: a commentary.
      aug:
        au:
          Gyamfi, Joyce
          Ojo, Temitope
          Iwelunmor, Juliet
          Ogedegbe, Gbenga
          Ryan, Nessa
          Diawara, Amy
          Nnodu, Obiageli
          Wonkam, Ambroise
          Royal, Charmaine
          Peprah, Emmanuel
        affil: Global Health Program and Department of Social and Behavioral Sciences, NYU School of Global Public Health, 14 East 4th Street, 3rd Fl, 10003, New York, NY, USA
      sug:
        subj:
          Anemia, Sickle Cell Therapy
          Medical Practice, Evidence-Based
          Quality of Life
          Africa
          Ferrans and Powers Quality of Life Index
      ab: Background: The burden of sickle cell disease (SCD) is greatest among African nations. Effective scalability of evidence-based interventions (e.g., newborn screening, health education, prophylaxis for infection, optimal nutrition and hydration, hydroxyurea therapy, blood transfusions, and transcranial Doppler (TCD) screening) is urgently needed particularly in these settings for disease management. However, Africa is constrained by limited resources and the lack of capacity to conduct implementation science research for proper understanding of context, and assessment of barriers and facilitators to the uptake and scalability of evidence-based interventions (EBI) for SCD management.Main Body: We outline implementation science approaches to embed EBI for SCD within the African context and highlight key implementation research programs for SCD management. Building implementation research capacity will meet the major need of developing effective life-long and accessible locally-tailored interventions for patients with SCD in Africa.Conclusion: This commentary communicates the importance of the application of implementation science methodology to scale-up evidence-based interventions for the management of SCD in order to reduce pain, prevent other morbidities and premature death experienced by people with SCD in Africa, and improve their overall quality of life.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Unknown
    language: English
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