Novel behavioural approaches and implementation science for mitigating genetic risk of cardiovascular disease due to elevated lipoprotein(a).
Purpose Of Review: Elevated lipoprotein(a) [Lp(a)] is a genetic trait that indicates higher risk of atherosclerotic cardiovascular disease (ASCVD). We review novel strategies to mitigate behavioural risk-factors in this genetic condition.Recent Findings: Pharmacological and biological interventions...
| Publicado en: | Current Opinion in Endocrinology, Diabetes & Obesity Vol. 28; no. 2; pp. 174 - 181 |
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| Autores principales: | , , , , , |
| Formato: | review Journal Article |
| Publicado: |
Lippincott Williams & Wilkins
Apr2021
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=148878611&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 148878611 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 1752296X 4Z2J jtl: Current Opinion in Endocrinology, Diabetes & Obesity issn: 1752296X maglogo: N pubinfo: dt: Apr2021 vid: 28 iid: 2 pid: 5086 pub: Lippincott Williams & Wilkins place: Baltimore, Maryland artinfo: ui: 148878611 148878611 NLM33395090 148878611 10.1097/MED.0000000000000609 NLM33395090 148878611 ppf: 174 ppct: 7 formats: tig: atl: Novel behavioural approaches and implementation science for mitigating genetic risk of cardiovascular disease due to elevated lipoprotein(a). aug: au: Mullan, Barbara Chan, Dick Charlesworth, Jessica Moullin, Joanna Schultz, Carl Watts, Gerald F. affil: Faculty of Health Sciences, School of Psychology, Curtin University, Bentley sug: subj: Cardiovascular Diseases Prevention and Control Hypercholesterolemia, Familial Cardiovascular Diseases Lipoproteins Risk Factors Scales ab: Purpose Of Review: Elevated lipoprotein(a) [Lp(a)] is a genetic trait that indicates higher risk of atherosclerotic cardiovascular disease (ASCVD). We review novel strategies to mitigate behavioural risk-factors in this genetic condition.Recent Findings: Pharmacological and biological interventions are available for lowering Lp(a). However, the acceptability and feasibility of these approaches are questionable due to cost and lack of clinical evidence for their efficacy. A number of low-cost, minimal patient contact interventions are available for modifying behavioural risk-factors that are associated with increased risk of ASCVD familial hypercholesterolaemia and diabetes. These include lifestyle interventions designed to improve diet and physical activity. These interventions may be particularly important among individuals with elevated Lp(a) to manage their higher risk of diabetes and ASCVD. The following article outlines recent research that has examined such low-cost, minimal patient contact interventions.Summary: The current research indicated that such interventions, which are grounded in psychological theory, can assist individuals to improve their diet and physical activity. These findings have implications for developing and implementing similar interventions for individuals with elevated Lp(a), so as to assist in reducing behavioural risk-factors associated with ASCVD. pubtype: Academic Journal doctype: review Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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