Clinical Outcomes of Male Subjects With Moderate COPD Based on Maximum Mid-Expiratory Flow.
BACKGROUND: Although FEV1 and FEV1/FVC are accepted as standard parameters in treatment follow-up, these parameters have a limited ability to predict clinical outcomes in patients with COPD. However, small airways dysfunction, which is determined by maximum mid-expiratory flow, is variable in the sa...
| Publicado en: | Respiratory Care Vol. 66; no. 3; pp. 442 - 449 |
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| Autores principales: | , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Mary Ann Liebert, Inc.
Mar2021
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=148893295&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 148893295 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00201324 4GG jtl: Respiratory Care issn: 00201324 maglogo: N pubinfo: dt: Mar2021 vid: 66 iid: 3 pid: 1365 pub: Mary Ann Liebert, Inc. place: New Rochelle, New York artinfo: ui: 148893295 148893295 148893295 10.4187/respcare.07794 148893295 ppf: 442 ppct: 7 formats: fmt: @attributes: type: P tig: atl: Clinical Outcomes of Male Subjects With Moderate COPD Based on Maximum Mid-Expiratory Flow. aug: au: Aktan, Ridvan Ozalevli, Sevgi Ozgen Alpaydin, Aylin affil: Department of Physiotherapy, Vocational School of Health Services, Izmir University of Economics, Izmir, Turkey sug: subj: Pulmonary Disease, Chronic Obstructive Fatigue Forced Expiratory Volume Physical Activity Dyspnea Severity of Illness Quality of Life Airway Obstruction Lung Physiology Human Cross Sectional Studies Multiple Regression Instrument by Type Scales Questionnaires Descriptive Statistics Vital Capacity T-Tests Chi Square Test Data Analysis Software Male Female Middle Age Aged Middle Aged: 45-64 years Aged: 65+ years Male Female ab: BACKGROUND: Although FEV1 and FEV1/FVC are accepted as standard parameters in treatment follow-up, these parameters have a limited ability to predict clinical outcomes in patients with COPD. However, small airways dysfunction, which is determined by maximum mid-expiratory flow, is variable in the same stage of patients with COPD, even if their FEV1 and FEV1/FVC are similar. The aim of this study was to compare pulmonary function, the severity of perceived dyspnea, the severity of fatigue, physical activity level, and health-related quality of life based on the severity of small airways dysfunction in male subjects with moderate COPD. METHODS: The study consisted of 96 subjects with moderate COPD. Pulmonary function tests, the distance achieved on the 6- min walk test, the modified Medical Research Council Dyspnea Scale, the International Physical Activity Questionnaire - short form, the Fatigue Severity Scale, the St George Respiratory Questionnaire, and Short Form 36 questionnaire were evaluated in all subjects. After calculating the mean percent of predicted maximum mid-expiratory flow for the entire sample, subjects were divided into 2 groups: below average (Group 1, n = 54 subjects) and above average (Group 2, n = 42 subjects). RESULTS: There were no differences between the groups in age, body mass index, cigarette consumption, percent of predicted FEV1, and FEV1 /FVC (P = .55, .61, .19, .09, and .15, respectively). Scores from the Fatigue Severity Scale and the modified Medical Research Council dyspnea scale were significantly higher in Group 1 (P = .003 and P = .002, respectively); in addition, results from the 6-min walk test and the International Physical Activity Questionnaire - short form scores were significantly lower (P = .001 and P < .001, respectively). CONCLUSIONS: Increased small airways dysfunction led to increased perception of dyspnea and fatigue, as well as poor exercise capacity and health-related quality of life in male subjects with COPD. We suggest that it may be useful to consider the maximum mid-expiratory flow in addition to FEV1 and FEV1/FVC in the treatment and follow-up of male patients with moderate COPD. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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