Direct comparison of multilayer left ventricular global longitudinal strain using CMR feature tracking and speckle tracking echocardiography.

Background: Cardiac magnetic resonance feature tracking (CMR-FT) and speckle tracking echocardiography (STE) are well-established strain imaging modalities. Multilayer strain measurement permits independent assessment of endocardial and epicardial strain. This novel and layer specific approach to ev...

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Published in:BMC Cardiovascular Disorders Vol. 21; no. 1; pp. 1 - 11
Main Authors: Ananthapadmanabhan, Saikrishna, Vo, Giau, Nguyen, Tuan, Dimitri, Hany, Otton, James
Format: research Journal Article
Published: BioMed Central 2/19/2021
Online Access:View this record in EBSCOhost
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      dt: 2/19/2021
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      pub: BioMed Central
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        148903343
        10.1186/s12872-021-01916-8
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        atl: Direct comparison of multilayer left ventricular global longitudinal strain using CMR feature tracking and speckle tracking echocardiography.
      aug:
        au:
          Ananthapadmanabhan, Saikrishna
          Vo, Giau
          Nguyen, Tuan
          Dimitri, Hany
          Otton, James
        affil: Faculty of Medicine, University of New South Wales, 2052, Sydney, Australia
      sug:
        subj:
          Magnetic Resonance Imaging
          Echocardiography
          Ventricular Function, Left
          Human
          Time Factors
          Reproducibility of Results
          Male
          Aged
          Predictive Value of Tests
          Prognosis
          Adult
          Female
          Middle Age
          Comparative Studies
          Multicenter Studies
          Evaluation Research
          Validation Studies
          Scales
          Aged: 65+ years
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Male
          Female
      ab: Background: Cardiac magnetic resonance feature tracking (CMR-FT) and speckle tracking echocardiography (STE) are well-established strain imaging modalities. Multilayer strain measurement permits independent assessment of endocardial and epicardial strain. This novel and layer specific approach to evaluating myocardial deformation parameters may provide greater insight into cardiac contractility when compared to whole-layer strain analysis. The aim of this study is to validate CMR-FT as a tool for multilayer strain analysis by providing a direct comparison between multilayer global longitudinal strain (GLS) values between CMR-FT and STE.Methods: We studied 100 patients who had an acute myocardial infarction (AMI), who underwent CMR imaging and echocardiogram at baseline and follow-up (48 ± 13 days). Dedicated tissue tracking software was used to analyse single- and multi-layer GLS values for CMR-FT and STE.Results: Correlation coefficients for CMR-FT and STE were 0.685, 0.687, and 0.660 for endocardial, epicardial, and whole-layer GLS respectively (all p < 0.001). Bland Altman analysis showed good inter-modality agreement with minimal bias. The absolute limits of agreement in our study were 6.4, 5.9, and 5.5 for endocardial, whole-layer, and epicardial GLS respectively. Absolute biases were 1.79, 0.80, and 0.98 respectively. Intraclass correlation coefficient (ICC) values showed moderate agreement with values of 0.626, 0.632, and 0.671 respectively (all p < 0.001).Conclusion: There is good inter-modality agreement between CMR-FT and STE for whole-layer, endocardial, and epicardial GLS, and although values should not be used interchangeably our study demonstrates that CMR-FT is a viable imaging modality for multilayer strain.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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