Uraemic Cardiomyopathy: A Review of Current Literature.
Uraemic Cardiomyopathy (UC) is recognised as an intricate and multifactorial disease which portends a significant burden in patients with End-Stage Renal Disease (ESRD). The cardiovascular morbidity and mortality associated with UC is significant and can be associated with the development of arrythm...
| Publicado en: | Clinical Medicine Insights: Cardiology Vol. 15; pp. 1 - 10 |
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| Autores principales: | , , , |
| Formato: | review tables/charts Journal Article |
| Publicado: |
Sage Publications Inc.
2/23/2021
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=148942135&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 148942135 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 11795468 B3KL jtl: Clinical Medicine Insights: Cardiology issn: 11795468 maglogo: Y pubinfo: dt: 2/23/2021 vid: 15 pid: 344 pub: Sage Publications Inc. place: Thousand Oaks, California artinfo: ui: 148942135 148942135 148942135 10.1177/1179546821998347 148942135 ppf: 1 ppct: 9 formats: fmt: @attributes: type: P tig: atl: Uraemic Cardiomyopathy: A Review of Current Literature. aug: au: Garikapati, Kartheek Goh, Daniel Khanna, Shaun Echampati, Krishna affil: Department of Internal Medicine, Toowoomba Hospital, Toowoomba, QLD, Australia sug: subj: Kidney Failure, Chronic Complications Uremia Physiopathology Myocardial Diseases Risk Factors Myocardial Diseases Diagnosis Myocardial Diseases Therapy Arrhythmia Heart Failure Death, Sudden, Cardiac Echocardiography Magnetic Resonance Imaging Hypertrophy, Left Ventricular Diagnosis Adrenergic beta-Antagonists Therapeutic Use Aldosterone Antagonists Therapeutic Use Hemodialysis Kidney Transplantation ab: Uraemic Cardiomyopathy (UC) is recognised as an intricate and multifactorial disease which portends a significant burden in patients with End-Stage Renal Disease (ESRD). The cardiovascular morbidity and mortality associated with UC is significant and can be associated with the development of arrythmias, cardiac failure and sudden cardiac death (SCD). The pathophysiology of UC involves a complex interplay of traditional implicative factors such as haemodynamic overload and circulating uraemic toxins as well as our evolving understanding of the Chronic Kidney Disease-Mineral Bone Disease pathway. There is an instrumental role for multi-modality imaging in the diagnostic process; including transthoracic echocardiography and cardiac magnetic resonance imaging in identifying the hallmarks of left ventricular hypertrophy and myocardial fibrosis that characterise UC. The appropriate utilisation of the aforementioned diagnostics in the ESRD population may help guide therapeutic approaches, such as pharmacotherapy including beta-blockers and aldosterone-antagonists as well as haemodialysis and renal transplantation. Despite this, there remains limitations in effective therapeutic interventions for UC and ongoing research on a cellular level is vital in establishing further therapies. pubtype: Academic Journal doctype: review tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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