Ankle fracture classification using deep learning: automating detailed AO Foundation/Orthopedic Trauma Association (AO/OTA) 2018 malleolar fracture identification reaches a high degree of correct classification.

Background and purpose — Classification of ankle fractures is crucial for guiding treatment but advanced classifications such as the AO Foundation/Orthopedic Trauma Association (AO/OTA) are often too complex for human observers to learn and use. We have therefore investigated whether an automated al...

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Publicado en:Acta Orthopaedica Vol. 92; no. 1; pp. 102 - 109
Autores principales: Olczak, Jakub, Emilson, Filip, Razavian, Ali, Antonsson, Tone, Stark, Andreas, Gordon, Max
Formato: diagnostic images equations & formulas research tables/charts Journal Article
Publicado: Medical Journals Sweden AB Feb2021
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Medical Journals Sweden AB
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        10.1080/17453674.2020.1837420
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        atl: Ankle fracture classification using deep learning: automating detailed AO Foundation/Orthopedic Trauma Association (AO/OTA) 2018 malleolar fracture identification reaches a high degree of correct classification.
      aug:
        au:
          Olczak, Jakub
          Emilson, Filip
          Razavian, Ali
          Antonsson, Tone
          Stark, Andreas
          Gordon, Max
        affil: Karolinska Institute, Institution for Clinical Sciences, Danderyd University Hospital, Stockholm, Sweden
      sug:
        subj:
          Ankle Fractures Classification
          Deep Learning
          Automation
          Foundations
          Orthopedics Organizations
          Orthopedic Care Standards
          Human
          Neural Networks (Computer)
          Computers and Computerization
          Ankle Radiography
          Descriptive Statistics
          Confidence Intervals
          Odds Ratio
      ab: Background and purpose — Classification of ankle fractures is crucial for guiding treatment but advanced classifications such as the AO Foundation/Orthopedic Trauma Association (AO/OTA) are often too complex for human observers to learn and use. We have therefore investigated whether an automated algorithm that uses deep learning can learn to classify radiographs according to the new AO/OTA 2018 standards. Method — We trained a neural network based on the ResNet architecture on 4,941 radiographic ankle examinations. All images were classified according to the AO/OTA 2018 classification. A senior orthopedic surgeon (MG) then re-evaluated all images with fractures. We evaluated the network against a test set of 400 patients reviewed by 2 expert observers (MG, AS) independently. Results — In the training dataset, about half of the examinations contained fractures. The majority of the fractures were malleolar, of which the type B injuries represented almost 60% of the cases. Average area under the area under the receiver operating characteristic curve (AUC) was 0.90 (95% CI 0.82–0.94) for correctly classifying AO/OTA class where the most common major fractures, the malleolar type B fractures, reached an AUC of 0.93 (CI 0.90–0.95). The poorest performing type was malleolar A fractures, which included avulsions of the fibular tip. Interpretation — We found that a neural network could attain the required performance to aid with a detailed ankle fracture classification. This approach could be scaled up to other body parts. As the type of fracture is an important part of orthopedic decision-making, this is an important step toward computer-assisted decision-making.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        equations & formulas
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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