Allele‐Specific Quantification of HLA–DRB1 Transcripts Reveals Imbalanced Allelic Expression That Modifies the Amino Acid Effects in HLA–DRβ1.

Objective: HLA association fine‐mapping studies have shown the effects of missense variants in HLA–DRB1 on rheumatoid arthritis (RA) susceptibility, prognosis, and autoantibody production. However, the phenotypic effects of expression changes in HLA–DRB1 remain poorly understood. Therefore, we inves...

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Publicado en:	Arthritis & Rheumatology Vol. 73; no. 3; pp. 381 - 392
Autores principales:	Chun, Sehwan, Bang, So‐Young, Ha, Eunji, Cui, Jing, Gu, Ki‐Nam, Lee, Hye‐Soon, Kim, Kwangwoo, Bae, Sang‐Cheol
Formato:	equations & formulas research tables/charts Journal Article
Publicado:	Wiley-Blackwell Mar2021
Acceso en línea:	Ver este registro en EBSCOhost