Counting human chromosomes before 1960: preconceptions, perceptions and predilections.
In 1956 the biomedical world was surprised to hear a report that human cells each contained forty six chromosomes, rather than the forty eight count that had been documented since the 1920s. Application of available techniques to culture human cells in vitro, halt their division at metaphase, and di...
| Publicado en: | Annals of Science Vol. 78; no. 1; pp. 92 - 117 |
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| Formato: | Artículo |
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Taylor & Francis Ltd
Jan2021
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=hlh&AN=149012887&site=ehost-live header: @attributes: shortDbName: hlh uiTerm: 149012887 longDbName: Humanities International Complete uiTag: AN controlInfo: bkinfo: jinfo: jid: 00033790 7J1 jtl: Annals of Science issn: 00033790 maglogo: Y pubinfo: dt: Jan2021 vid: 78 iid: 1 pid: 377 pub: Taylor & Francis Ltd artinfo: ui: 149012887 10.1080/00033790.2020.1854854 ppf: 92 ppct: 25 formats: fmt: – @attributes: type: T – @attributes: type: P size: 1.6MB tig: atl: Counting human chromosomes before 1960: preconceptions, perceptions and predilections. aug: au: Rushton, Alan R. affil: Department of Pediatrics, Hunterdon Medical Center, Flemington, NJ, USA su: Biomedical materials Human chromosomes Human genetics Human cytogenetics Conformity Morphology sug: subj: Biomedical materials Human chromosomes Human genetics Human cytogenetics Conformity Morphology keyword: human cytogenetics preconceptions in biological research social conformity in biological research visual perspective in science ab: In 1956 the biomedical world was surprised to hear a report that human cells each contained forty six chromosomes, rather than the forty eight count that had been documented since the 1920s. Application of available techniques to culture human cells in vitro, halt their division at metaphase, and disperse chromosomes in an optical plane permitted perception of visual images not seen before. Researchers continued to obtain the preconceived forty eight counts until reeducation with these novel epistemic 'chromosomes' convinced them that they could confidently report forty six chromosomes per cell. Within only a few years, and virtually without dissent, the social community of human cytogeneticists agreed upon a shared visual culture of human chromosome count and morphology. The initial forty six count proved not to be an anomaly. A new comparison of historical and ethnomethodological studies has suggested a better understanding of how applied technologies coupled with altered human perceptions established a new science. Human cytogenetics then collaborated with medical genetics to correlate changes in the new human karyotype with disorders of clinical significance. pubtype: Academic Journal doctype: Article src: R language: English refInfo: copyright: @attributes: flag: Y custom: Copyright of Annals of Science is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. item: Annals of Science holder: Taylor & Francis Ltd dt: @attributes: year: 2021 holdings: @attributes: islocal: N |
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