Optimal sampling strategies for darunavir and external validation of the underlying population pharmacokinetic model.

Purpose: A variety of diagnostic methods are available to validate the performance of population pharmacokinetic models. Internal validation, which applies these methods to the model building dataset and to additional data generated through Monte Carlo simulations, is often sufficient, but external...

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Detalles Bibliográficos
Publicado en:European Journal of Clinical Pharmacology Vol. 77; no. 4; pp. 607 - 617
Autores principales: Stillemans, Gabriel, Belkhir, Leila, Vandercam, Bernard, Vincent, Anne, Haufroid, Vincent, Elens, Laure
Formato: equations & formulas research tables/charts Journal Article
Publicado: Springer Nature Apr2021
Acceso en línea:Ver este registro en EBSCOhost