Recent evolutions of machine learning applications in clinical laboratory medicine.

Machine learning (ML) is gaining increased interest in clinical laboratory medicine, mainly triggered by the decreased cost of generating and storing data using laboratory automation and computational power, and the widespread accessibility of open source tools. Nevertheless, only a handful of ML-ba...

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Publicado en:Critical Reviews in Clinical Laboratory Sciences Vol. 58; no. 2; pp. 131 - 153
Autores principales: De Bruyne, Sander, Speeckaert, Marijn M., Van Biesen, Wim, Delanghe, Joris R.
Formato: pictorial review tables/charts Journal Article
Publicado: Taylor & Francis Ltd Mar2021
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Mar2021
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      pub: Taylor & Francis Ltd
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        atl: Recent evolutions of machine learning applications in clinical laboratory medicine.
      aug:
        au:
          De Bruyne, Sander
          Speeckaert, Marijn M.
          Van Biesen, Wim
          Delanghe, Joris R.
        affil: Department of Diagnostic Sciences, Ghent University, Ghent, Belgium
      sug:
        subj:
          Machine Learning Utilization
          Clinical Laboratories Trends
          Medicine
          Workflow
          Algorithms
          Technology, Medical
          Artificial Intelligence
          Automation, Laboratory
          Quality Assessment
          Urinalysis
          Biochemistry
          Sensitivity and Specificity
          Hematology
          Microbiology
          Workload
          Chlamydiales Analysis
          Drug Resistance, Microbial Evaluation
          Diagnosis, Laboratory
      ab: Machine learning (ML) is gaining increased interest in clinical laboratory medicine, mainly triggered by the decreased cost of generating and storing data using laboratory automation and computational power, and the widespread accessibility of open source tools. Nevertheless, only a handful of ML-based products are currently commercially available for routine clinical laboratory practice. In this review, we start with an introduction to ML by providing an overview of the ML landscape, its general workflow, and the most commonly used algorithms for clinical laboratory applications. Furthermore, we aim to illustrate recent evolutions (2018 to mid-2020) of the techniques used in the clinical laboratory setting and discuss the associated challenges and opportunities. In the field of clinical chemistry, the reviewed applications of ML algorithms include quality review of lab results, automated urine sediment analysis, disease or outcome prediction from routine laboratory parameters, and interpretation of complex biochemical data. In the hematology subdiscipline, we discuss the concepts of automated blood film reporting and malaria diagnosis. At last, we handle a broad range of clinical microbiology applications, such as the reduction of diagnostic workload by laboratory automation, the detection and identification of clinically relevant microorganisms, and the detection of antimicrobial resistance.
      pubtype: Academic Journal
      doctype:
        pictorial
        review
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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