Neurotoxicity of Ortho-Phthalates: Recommendations for Critical Policy Reforms to Protect Brain Development in Children.

Robust data from longitudinal birth cohort studies and experimental studies of perinatally exposed animals indicate that exposure to ortho-phthalates can impair brain development and increase risks for learning, attention, and behavioral disorders in childhood. This growing body of evidence, along w...

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Publicado en:American Journal of Public Health Vol. 111; no. 4; pp. 687 - 696
Autores principales: Engel, Stephanie M., Patisaul, Heather B., Brody, Charlotte, Hauser, Russ, Zota, Ami R., Bennet, Deborah H., Swanson, Maureen, Whyatt, Robin M.
Formato: Artículo
Publicado: American Public Health Association Apr2021
Materias:
Acceso en línea:Ver este registro en EBSCOhost
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      pub: American Public Health Association
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        atl: Neurotoxicity of Ortho-Phthalates: Recommendations for Critical Policy Reforms to Protect Brain Development in Children.
      aug:
        au:
          Engel, Stephanie M.
          Patisaul, Heather B.
          Brody, Charlotte
          Hauser, Russ
          Zota, Ami R.
          Bennet, Deborah H.
          Swanson, Maureen
          Whyatt, Robin M.
      su:
        Child development
        Public health
        Government regulation
        Brain physiology
        Health care reform
        Neural development
        Phthalate esters
      sug:
        subj:
          Child development
          Public health
          Government regulation
          Health and Welfare Funds
          Brain physiology
          Health care reform
          Neural development
          Phthalate esters
      ab: Robust data from longitudinal birth cohort studies and experimental studies of perinatally exposed animals indicate that exposure to ortho-phthalates can impair brain development and increase risks for learning, attention, and behavioral disorders in childhood. This growing body of evidence, along with known adverse effects on male reproductive tract development, calls for immediate action. Exposures are ubiquitous; the majority of people are exposed to multiple ortho-phthalates simultaneously. We thus recommend that a class approach be used in assessing health impacts as has been done with other chemical classes. We propose critically needed policy reforms to eliminate ortho-phthalates from products that lead to exposure of pregnant women, women of reproductive age, infants, and children. Specific attention should be focused on reducing exposures among socially vulnerable populations such as communities of color, who frequently experience higher exposures. Ortho-phthalates are used in a vast array of products and elimination will thus necessitate a multipronged regulatory approach at federal and state levels. The fact that manufacturers and retailers have already voluntarily removed ortho-phthalates from a wide range of products indicates that this goal is feasible.
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    language: English
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