Prophylactic Antibiotics for Urinary Tract Infections after Urodynamic Studies: A Meta-Analysis.
Aim. We aimed to perform a meta-analysis to determine whether antibiotic prophylaxis reduces the incidence of urinary tract infections (UTIs) after urodynamic studies (UDS). Methods. We conducted a systematic search of PubMed, Web of Science, Ovid, Elsevier, ClinicalKey, Embase, Cochrane Library, Me...
| Published in: | BioMed Research International pp. 1 - 10 |
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| Main Authors: | , , , , , |
| Format: | research systematic review tables/charts Journal Article |
| Published: |
Wiley-Blackwell
2/28/2021
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=149334775&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 149334775 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 23146133 FT2T jtl: BioMed Research International issn: 23146133 maglogo: N pubinfo: dt: 2/28/2021 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 149334775 149334775 149334775 10.1155/2021/6661588 149334775 ppf: 1 ppct: 9 formats: fmt: @attributes: type: P tig: atl: Prophylactic Antibiotics for Urinary Tract Infections after Urodynamic Studies: A Meta-Analysis. aug: au: Wu, Xiao-yu Cheng, Yu Xu, Sheng-fei Ling, Qing Yuan, Xiao-yi Du, Guang-hui affil: Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, China sug: subj: Antibiotic Prophylaxis Urinary Tract Infections Epidemiology Urodynamics Evaluation Urinary Tract Infections Prevention and Control Human Systematic Review Meta Analysis PubMed Embase Cochrane Library Medline Randomized Controlled Trials Placebos Software Bacteriuria Risk Factors Urinary Tract Infections Risk Factors ab: Aim. We aimed to perform a meta-analysis to determine whether antibiotic prophylaxis reduces the incidence of urinary tract infections (UTIs) after urodynamic studies (UDS). Methods. We conducted a systematic search of PubMed, Web of Science, Ovid, Elsevier, ClinicalKey, Embase, Cochrane Library, Medline, and Wiley Online Library. Randomized controlled trials (RCTs) comparing the effectiveness of prophylactic antibiotics with placebo or no treatment in preventing UTI after UDS were included. Two reviewers extracted data independently, and RevMan 5.3 software was used to analyze relative risk (RR) with 95% confidence intervals (CI). Heterogeneity was assessed by the Q test and I 2 test. Results. The final meta-analysis included 1829 patients in 13 RCTs. Compared with the placebo or no treatment group, prophylactic antibiotics could significantly reduce the risk of bacteriuria (RR = 0.42 , 95% CI: 0.30-0.60) and the risk of symptomatic UTI (RR = 0.65 , 95% CI: 0.48-0.88). In addition, there was no statistically significant difference in the risk of adverse events (RR = 4.93 , 95% CI: 0.61-40.05). No significant heterogeneity or publication bias was found in this study. Conclusions. Current evidence showed that prophylactic antibiotics could reduce the risk of asymptomatic bacteriuria and symptomatic UTI after UDS without increasing the incidence of adverse events. pubtype: Academic Journal doctype: meta analysis research systematic review tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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