Comparison of Multispectral Image-Processing Methods for Brain Tissue Classification in BrainWeb Synthetic Data and Real MR Images.

Accurate quantification of brain tissue is a fundamental and challenging task in neuroimaging. Over the past two decades, statistical parametric mapping (SPM) and FMRIB's Automated Segmentation Tool (FAST) have been widely used to estimate gray matter (GM) and white matter (WM) volumes. However, the...

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Publicado en:BioMed Research International pp. 1 - 13
Autores principales: Chen, Hsian-Min, Chen, Hung-Chieh, Chen, Clayton Chi-Chang, Chang, Yung-Chieh, Wu, Yi-Ying, Chen, Wen-Hsien, Sung, Chiu-Chin, Chai, Jyh-Wen, Lee, San-Kan
Formato: diagnostic images research tables/charts Journal Article
Publicado: Wiley-Blackwell 3/8/2021
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 3/8/2021
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1155/2021/9820145
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        atl: Comparison of Multispectral Image-Processing Methods for Brain Tissue Classification in BrainWeb Synthetic Data and Real MR Images.
      aug:
        au:
          Chen, Hsian-Min
          Chen, Hung-Chieh
          Chen, Clayton Chi-Chang
          Chang, Yung-Chieh
          Wu, Yi-Ying
          Chen, Wen-Hsien
          Sung, Chiu-Chin
          Chai, Jyh-Wen
          Lee, San-Kan
        affil: Center for QUantitative Imaging in Medicine (CQUIM), Department of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan
      sug:
        subj:
          Image Processing, Computer Assisted Methods
          Magnetic Resonance Imaging
          Brain Physiology
          Algorithms Utilization
          Human
          Adult
          Middle Age
          Aged
          Aged, 80 and Over
          Cerebrospinal Fluid Analysis
          Volunteer Workers
          Descriptive Statistics
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Aged: 65+ years
          Aged, 80 & over
      ab: Accurate quantification of brain tissue is a fundamental and challenging task in neuroimaging. Over the past two decades, statistical parametric mapping (SPM) and FMRIB's Automated Segmentation Tool (FAST) have been widely used to estimate gray matter (GM) and white matter (WM) volumes. However, they cannot reliably estimate cerebrospinal fluid (CSF) volumes. To address this problem, we developed the TRIO algorithm (TRIOA), a new magnetic resonance (MR) multispectral classification method. SPM8, SPM12, FAST, and the TRIOA were evaluated using the BrainWeb database and real magnetic resonance imaging (MRI) data. In this paper, the MR brain images of 140 healthy volunteers (51.5 ± 15.8 y / o) were obtained using a whole-body 1.5 T MRI system (Aera, Siemens, Erlangen, Germany). Before classification, several preprocessing steps were performed, including skull stripping and motion and inhomogeneity correction. After extensive experimentation, the TRIOA was shown to be more effective than SPM and FAST. For real data, all test methods revealed that the participants aged 20–83 years exhibited an age-associated decline in GM and WM volume fractions. However, for CSF volume estimation, SPM8-s and SPM12-m both produced different results, which were also different compared with those obtained by FAST and the TRIOA. Furthermore, the TRIOA performed consistently better than both SPM and FAST for GM, WM, and CSF volume estimation. Compared with SPM and FAST, the proposed TRIOA showed more advantages by providing more accurate MR brain tissue classification and volume measurements, specifically in CSF volume estimation.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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