Therapeutic Potential of RTA 404 in Human Brain Malignant Glioma Cell Lines via Cell Cycle Arrest via p21/AKT Signaling.

Background. Glioblastoma multiforme (GBM) is the most common malignant brain tumor in the world. Despite advances in surgical resection, radiotherapy, and chemotherapy, GBM continues to have a poor overall survival. CDDO (2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid), a synthetic triterpenoid, is an...

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Publicado en:	BioMed Research International pp. 1 - 16
Autores principales:	Tsai, Tai-Hsin, Lieu, Ann-Shung, Wang, Yi-Wen, Yang, Sheau-Fang, Hsu, Yi-Chiang, Lin, Chih-Lung
Formato:	pictorial research tables/charts Journal Article
Publicado:	Wiley-Blackwell 3/9/2021
Acceso en línea:	Ver este registro en EBSCOhost