Usefulness of TI-scout images in the assessment of late gadolinium enhancement in children.

Background: Cardiovascular magnetic resonance (CMR) late gadolinium enhancement (LGE) requires identification of the normal myocardial nulling time using inversion time (TI)-scout imaging sequence. Although TI-scout images are not primarily used for myocardial assessment, they provide information re...

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Published in:Journal of Cardiovascular Magnetic Resonance (Elsevier B.V. ) Vol. 23; no. 1; pp. 1 - 10
Main Authors: Bannan, Badr, Aguet, Julien, House, Aswathy Vaikom, Gill, Navjot, Tassos, Vivian P., Amirabadi, Afsaneh, Seed, Mike, Lam, Christopher Z., Yoo, Shi-Joon
Format: research tables/charts Journal Article
Published: Elsevier B.V. 3/18/2021
Online Access:View this record in EBSCOhost
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      dt: 3/18/2021
      vid: 23
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      pub: Elsevier B.V.
      place: New York, New York
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        149335663
        149335663
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        10.1186/s12968-021-00719-2
        149335663
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        atl: Usefulness of TI-scout images in the assessment of late gadolinium enhancement in children.
      aug:
        au:
          Bannan, Badr
          Aguet, Julien
          House, Aswathy Vaikom
          Gill, Navjot
          Tassos, Vivian P.
          Amirabadi, Afsaneh
          Seed, Mike
          Lam, Christopher Z.
          Yoo, Shi-Joon
        affil: Department of Diagnostic Imaging, The Hospital for Sick Children, University of Toronto, 555 University Avenue, M5G1X8, Toronto, ON, Canada
      sug:
        subj:
          Magnetic Resonance Imaging
          Image Enhancement
          Cardiovascular Diseases Diagnosis
          Cardiovascular Diseases Diagnosis
          Human
          Cardiac Patients
          Male
          Female
          Infant
          Child, Preschool
          Child
          Adolescence
          Cardiomyopathy, Hypertrophic Diagnosis
          Descriptive Statistics
          Infant: 1-23 months
          Child, Preschool: 2-5 years
          Child: 6-12 years
          Adolescent: 13-18 years
          Male
          Female
      ab: Background: Cardiovascular magnetic resonance (CMR) late gadolinium enhancement (LGE) requires identification of the normal myocardial nulling time using inversion time (TI)-scout imaging sequence. Although TI-scout images are not primarily used for myocardial assessment, they provide information regarding different signal recovery patterns of normal and abnormal myocardium facilitating identification of LGE in instances where standard LGE images alone are not diagnostic. We aimed to assess the diagnostic performance of TI-scout as compared to that of standard LGE images. Methods: CMR studies with LGE imaging in 519 patients (345 males, 1–17 years) were reviewed to assess the diagnostic performance of LGE imaging in terms of the location of LGE and the pathologic entities. The diagnostic performance of the TI-scout and standard LGE imaging was classified into four categories: (1) equally diagnostic, (2) TI-scout superior to standard LGE, (3) standard LGE superior to TI-scout, and (4) complementary, by the consensus of the two observers. Results: The study cohort consisted of 440 patients with negative LGE and 79 with evidence for LGE. For a negative diagnosis of LGE, TI-scout and standard LGE images were equally diagnostic in 75% of the cases and were complementary in 12%. For patients with LGE, TI-scout images were superior to standard LGE images in 52% of the cases and were complementary in 19%. The diagnostic performance of TI-scout images was superior to that of standard LGE images in all locations. TI-scout images were superior to standard LGE images in 11 of 12 (92%) cases with LGE involving the papillary muscles, in 7 /12 (58%) cases with subendocardial LGE, and in 4/7 (57%) cases with transmural LGE. TI-scout images were particularly useful assessing the presence and extent of LGE in hypertrophic cardiomyopathy (HCM). TI-scout was superior to standard LGE in 6/10 (60%) and was complementary in 3/10 (30%) of the positive cases with HCM. Conclusions: TI-scout images enhance the diagnostic performance of LGE imaging in children.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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