Artificial Intelligence Improves the Accuracy in Histologic Classification of Breast Lesions.

Objectives: This study evaluated the usefulness of artificial intelligence (AI) algorithms as tools in improving the accuracy of histologic classification of breast tissue.Methods: Overall, 100 microscopic photographs (test A) and 152 regions of interest in whole-slide images (test B) of breast tiss...

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Publicado en:American Journal of Clinical Pathology Vol. 155; no. 4; pp. 527 - 537
Autores principales: Polónia, António, Campelos, Sofia, Ribeiro, Ana, Aymore, Ierece, Pinto, Daniel, Biskup-Fruzynska, Magdalena, Veiga, Ricardo Santana, Canas-Marques, Rita, Aresta, Guilherme, Araújo, Teresa, Campilho, Aurélio, Kwok, Scotty, Aguiar, Paulo, Eloy, Catarina
Formato: pictorial research tables/charts Journal Article
Publicado: Oxford University Press / USA Apr2021
Acceso en línea:Ver este registro en EBSCOhost
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      jtl: American Journal of Clinical Pathology
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      dt: Apr2021
      vid: 155
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      pub: Oxford University Press / USA
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        10.1093/ajcp/aqaa151
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        atl: Artificial Intelligence Improves the Accuracy in Histologic Classification of Breast Lesions.
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          Polónia, António
          Campelos, Sofia
          Ribeiro, Ana
          Aymore, Ierece
          Pinto, Daniel
          Biskup-Fruzynska, Magdalena
          Veiga, Ricardo Santana
          Canas-Marques, Rita
          Aresta, Guilherme
          Araújo, Teresa
          Campilho, Aurélio
          Kwok, Scotty
          Aguiar, Paulo
          Eloy, Catarina
        affil: Department of Pathology, Ipatimup Diagnostics, Institute of Molecular Pathology and Immunology, University of Porto , Porto, Portugal
      sug:
        subj:
          Diagnosis, Computer Assisted Methods
          Breast Neoplasms Classification
          Artificial Intelligence
          Breast Neoplasms Pathology
          Image Interpretation, Computer Assisted Methods
          Female
          Human
          Comparative Studies
          Multicenter Studies
          Evaluation Research
          Validation Studies
          Female
      ab: Objectives: This study evaluated the usefulness of artificial intelligence (AI) algorithms as tools in improving the accuracy of histologic classification of breast tissue.Methods: Overall, 100 microscopic photographs (test A) and 152 regions of interest in whole-slide images (test B) of breast tissue were classified into 4 classes: normal, benign, carcinoma in situ (CIS), and invasive carcinoma. The accuracy of 4 pathologists and 3 pathology residents were evaluated without and with the assistance of algorithms.Results: In test A, algorithm A had accuracy of 0.87, with the lowest accuracy in the benign class (0.72). The observers had average accuracy of 0.80, and most clinically relevant discordances occurred in distinguishing benign from CIS (7.1% of classifications). With the assistance of algorithm A, the observers significantly increased their average accuracy to 0.88. In test B, algorithm B had accuracy of 0.49, with the lowest accuracy in the CIS class (0.06). The observers had average accuracy of 0.86, and most clinically relevant discordances occurred in distinguishing benign from CIS (6.3% of classifications). With the assistance of algorithm B, the observers maintained their average accuracy.Conclusions: AI tools can increase the classification accuracy of pathologists in the setting of breast lesions.
      pubtype: Academic Journal
      doctype:
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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