Lung Function of Children Following an Intensive Care Unit Admission for Asthma.
Background: To determine the lung function of children admitted to the intensive care unit (ICU) for a severe asthma exacerbation in the medium- to long-term following hospital discharge. Methods: We performed a retrospective chart review of children ≥6 years of age admitted to the ICU for a severe...
| Publicado en: | Pediatric Allergy, Immunology & Pulmonology Vol. 34; no. 1; pp. 1 - 7 |
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| Autores principales: | , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Mary Ann Liebert, Inc.
Mar2021
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=149380596&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 149380596 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 2151321X B9EX jtl: Pediatric Allergy, Immunology & Pulmonology issn: 2151321X maglogo: N pubinfo: dt: Mar2021 vid: 34 iid: 1 pid: 1365 pub: Mary Ann Liebert, Inc. place: New Rochelle, New York artinfo: ui: 149380596 149380596 149380596 10.1089/ped.2020.1271 149380596 ppf: 1 ppct: 6 formats: tig: atl: Lung Function of Children Following an Intensive Care Unit Admission for Asthma. aug: au: Major, Sandrine Vézina, Kevin Tse, Sze Man affil: Faculty of Medicine, McGill University, Montreal, Canada. sug: subj: Lung Physiopathology Lung Physiopathology Respiratory Mechanics Evaluation Asthma Prognosis Disease Exacerbation Asthma Therapy Severity of Illness Disease Exacerbation Therapy Intensive Care Units Patient Discharge Human Retrospective Design Record Review Child Adolescence Tertiary Health Care Hospitals Outpatients After Care Prospective Studies Descriptive Statistics Respiratory Function Tests Forced Expiratory Volume Vital Capacity Spirometry Paired T-Tests Forced Expiratory Flow Rates Respiratory Therapy Critical Care Length of Stay Male Female Sex Factors Child: 6-12 years Adolescent: 13-18 years Male Female ab: Background: To determine the lung function of children admitted to the intensive care unit (ICU) for a severe asthma exacerbation in the medium- to long-term following hospital discharge. Methods: We performed a retrospective chart review of children ≥6 years of age admitted to the ICU for a severe asthma exacerbation at a tertiary care center from January 1, 2000, to December 31, 2013. Lung function was ascertained during outpatient follow-up visits at 3–12 months and 12–24 months postdischarge. A total of 72 subjects met the inclusion criteria. Results: Subjects were predominantly boys (56.9%) and had a mean (standard deviation [SD]) age at admission of 10.3 years (3.4 years). The median (interquartile range) length of stay in the ICU was 1 day (1–3 days). Thirty-eight and 28 subjects performed pulmonary function tests with acceptable technique at the 3–12 months and 12–24 months postdischarge visits, respectively. At 3–12 months, the mean (SD) predicted forced expiratory volume in 1 s (FEV1) and forced expiratory flow between 25% and 75% of vital capacity (FEF25–75) percent were 95.9 (16.7) and 76.7 (25.8), respectively, and 97.4 (17.6) and 70.5 (24.9), respectively, at 12–24 months. FEV1/forced vital capacity (FEV1/FVC) was 81.7 (8.3) at 3–12 months and 79.3 (7.7) at 12–24 months. A paired t-test on 20 subjects who performed acceptable spirometry at both visits showed a significant intraindividual decrease in FEV1 (P = 0.008), FEF25–75 (P = 0.02), and FEV1/FVC (P = 0.01) between the 2 time points. Conclusion: Although prospective studies are required to confirm our findings, our study suggests that children admitted to the ICU for severe asthma exacerbations may be at risk for declining pulmonary function in the medium- to long-term postdischarge. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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