Investigating attention‐deficit hyperactivity disorder and autism spectrum disorder traits in the general population: What happens in adult life?
Background: Attention‐deficit hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) are generally considered early‐onset disorders so most research has therefore tended to focus on children. Differences between ADHD/ASD in adult life and childhood have been noted, but few population‐based...
| Publicado en: | Journal of Child Psychology & Psychiatry Vol. 62; no. 4; pp. 449 - 458 |
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| Autores principales: | , , , , , , , , |
| Formato: | Artículo |
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Wiley-Blackwell
Apr2021
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| Materias: | |
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ssf&AN=149411473&site=ehost-live header: @attributes: shortDbName: ssf uiTerm: 149411473 longDbName: Social Sciences Full Text (H.W. Wilson) uiTag: AN controlInfo: bkinfo: jinfo: jid: 00219630 JYY jtl: Journal of Child Psychology & Psychiatry issn: 00219630 maglogo: Y pubinfo: dt: Apr2021 vid: 62 iid: 4 pid: 480 pub: Wiley-Blackwell artinfo: ui: 149411473 10.1111/jcpp.13297 ppf: 449 ppct: 9 formats: tig: atl: Investigating attention‐deficit hyperactivity disorder and autism spectrum disorder traits in the general population: What happens in adult life? aug: au: Riglin, Lucy Leppert, Beate Langley, Kate Thapar, Ajay K. O'Donovan, Michael C. Davey Smith, George Stergiakouli, Evie Tilling, Kate Thapar, Anita affil: Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK School of Psychology, Cardiff University, Cardiff, UK su: United Kingdom Mental illness risk factors Self-evaluation Attention-deficit hyperactivity disorder Communicative disorders Sex distribution Autism Learning disabilities Disease risk factors Cognition disorder risk factors Secondary analysis sug: subj: Mental illness risk factors Self-evaluation Attention-deficit hyperactivity disorder Communicative disorders Sex distribution Autism Learning disabilities Disease risk factors United Kingdom Cognition disorder risk factors Secondary analysis keyword: adult attention‐deficit hyperactivity disorder autism spectrum disorder Avon Longitudinal Study of Parents and Children genetic Neurodevelopmental adult attention‐deficit hyperactivity disorder autism spectrum disorder Avon Longitudinal Study of Parents and Children genetic Neurodevelopmental ab: Background: Attention‐deficit hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) are generally considered early‐onset disorders so most research has therefore tended to focus on children. Differences between ADHD/ASD in adult life and childhood have been noted, but few population‐based studies have examined them in adulthood. Furthermore, the interpretation of findings is hampered by changes in measure and from parent report to self‐report. Method: We examined continuous/trait measures of parent‐ and self‐rated ADHD and ASD in adulthood (age 25 years) in a UK prospective longitudinal sample ALPSAC (the Avon Longitudinal Study of Parents and Children), using many of the same measures that parents reported on in childhood (N = 6,064). Our aim was to investigate these traits in this population for mean‐level sex differences, overlaps with other cognitive, learning and communication problems and their associations with polygenic risk scores (PRS) for neuropsychiatric disorders (ADHD, ASD, schizophrenia, depression and anxiety). Results: ADHD and ASD traits in adulthood, as in childhood, showed associations with childhood cognitive, learning and communication problems and adult communication/language measures, although less so for self‐ratings than parent‐ratings. Males had higher ADHD and ASD trait levels, but this was not as marked as in childhood. In adulthood, ADHD (both parent‐ and self‐rated) and ASD (parent‐rated) symptoms showed associations with ADHD PRS; self‐reported ADHD also showed association with depression PRS, whereas self‐reported ASD did not show strong PRS associations. Conclusions: Our findings suggest that in young adults, ADHD and ASD symptoms have similar characteristics as they do in childhood. Associations with other cognitive, learning and communication problems, and ADHD PRS were somewhat less pronounced for self‐reported adult ADHD and ASD symptoms, suggesting that even at age 25, parent reports, where available, could be clinically useful. pubtype: Academic Journal doctype: Article src: R language: English refInfo: copyright: @attributes: flag: N holdings: @attributes: islocal: N |
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