Quantitative assessment and determinants of the papillary microvasculature in healthy subjects.
Background: It is critical to monitor the optic disc's vessel density using Optical coherence tomography angiography (OCTA) and evaluate its determinants. In the current study, we investigate the superficial vessel density (VD) of the papillary microvasculature and its determinants in healthy subjec...
| Publicado en: | BMC Ophthalmology Vol. 21; no. 1; pp. 1 - 9 |
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| Autores principales: | , , , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
BioMed Central
3/20/2021
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=149418536&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 149418536 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 14712415 1CIB jtl: BMC Ophthalmology issn: 14712415 maglogo: N pubinfo: dt: 3/20/2021 vid: 21 iid: 1 pid: 24147 pub: BioMed Central artinfo: ui: 149418536 149418536 NLM33743618 149418536 10.1186/s12886-021-01896-5 NLM33743618 149418536 ppf: 1 ppct: 8 formats: tig: atl: Quantitative assessment and determinants of the papillary microvasculature in healthy subjects. aug: au: Zhou, Li-jun Luo, Xiu-zhi Shen, Pei-yang Li, Xin Su, Peng Zhu, Zhe Yan, Shi-gang Kong, Xiang-bin Lu, Xiao-he affil: Department of Ophthalmology, Zhujiang Hospital, Southern Medical University, 515282, Guangzhou, China sug: subj: Retina Tomography, Optical Coherence Cross Sectional Studies Prospective Studies China Blood Vessels Research Subjects Angiography Human ab: Background: It is critical to monitor the optic disc's vessel density using Optical coherence tomography angiography (OCTA) and evaluate its determinants. In the current study, we investigate the superficial vessel density (VD) of the papillary microvasculature and its determinants in healthy subjects of Southern China.Methods: This was a prospective, cross-sectional study. Superficial VD in healthy individuals' optic disc region was measured by OCTA. The factors associated with ocular and systemic parameters were analyzed using a generalized estimation equation (GEE) model.Results: A total of 510 eyes of 260 healthy subjects were analyzed in the study. The total VD in the optic disc area was 17.21 ± 2.15 mm- 1 (95% CI, 17.02-17.40 mm- 1). The VD in the inner ring and the outer ring of the optic disc were significantly higher compared with the central ring, while the VD of the superior quadrant and inferior quadrant was significantly higher compared with the temporal and nasal quadrant. After adjusting for the ocular factors and systemic factors, AL (β = - 0.4917, P = 0.0003), disc area (β = - 0.3748, P = 0.0143), CMT (β = - 0.0183, P = 0.0003) and SSI (β = 1.0588, P < 0.001) were significantly associated with total VD of the optic disc.Conclusion: The mean total VD in the optic disc area was 17.21 ± 2.15 mm- 1 in healthy subjects, and the superior and inferior VD was significantly higher than the temporal and nasal VD. AL, disc area, CMT, and SSI may affect the total VD in the optic disc area and should be considered in clinical practice. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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