Diffusion tensor imaging (tractography) in elderly people with dementia type Alzheimer's disease and mixed dementia.
Objective: The objective of the study was to evaluate the characteristics of white matter tracts by diffusion tensor imaging (tractography) in elderly people with dementia type Alzheimer's disease (AD) and mixed dementia through the measurements of fractional anisotropy (FA) and mean diffusivity (MD...
| Publicado en: | Revista Mexicana de Neurociencia Vol. 22; no. 2; pp. 42 - 51 |
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| Autores principales: | , , , , , |
| Formato: | Artículo |
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Academia Mexicana de Neurologia
Mar/Apr2021
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=lth&AN=149429473&site=ehost-live header: @attributes: shortDbName: lth uiTerm: 149429473 longDbName: MedicLatina uiTag: AN controlInfo: bkinfo: jinfo: jid: 16655044 R1Q jtl: Revista Mexicana de Neurociencia issn: 16655044 maglogo: N pubinfo: dt: Mar/Apr2021 vid: 22 iid: 2 pid: 20851 pub: Academia Mexicana de Neurologia artinfo: ui: 149429473 10.24875/RMN.20000106 ppf: 42 ppct: 9 formats: fmt: @attributes: type: P size: 466KB tig: atl: Diffusion tensor imaging (tractography) in elderly people with dementia type Alzheimer's disease and mixed dementia. aug: au: Bombón-Albán, Paulina E. Mimenza-Alvarado, Alberto J. Marrufo-Meléndez, Oscar R. Rubalcava-Ortega, Johnatan Gutiérrez-Gutiérrez, Lidia A. Aguilar-Navarro, Sara G. affil: Departament of Neurology, Neuromedicenter, Quito, Ecuador Departament of Geriatrics, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán (INCMyNSZ), Mexico City Departament of Neuroimaging, Instituto Nacional de Neurología y Neurocirugía Manuel Velasco Suárez, Mexico City Departament of Neuroimaging, INCMyNSZ, Mexico City Departament of Neurology, INCMyNSZ, Mexico City Departament of Geriatrics, INCMyNSZ, Mexico City. Mexico su: Diffusion tensor imaging Dementia Alzheimer's disease Health of older people Neuropsychology sug: subj: Diffusion tensor imaging Dementia Alzheimer's disease Health of older people Neuropsychology keyword: Fractional anisotropy Mean diffusivity Mixed dementia Tractography ab: Objective: The objective of the study was to evaluate the characteristics of white matter tracts by diffusion tensor imaging (tractography) in elderly people with dementia type Alzheimer's disease (AD) and mixed dementia through the measurements of fractional anisotropy (FA) and mean diffusivity (MD). Methods: Eight patients with AD and eight patients with mixed dementia were studied. Clinical, cognitive, and neuroimaging evaluation was carried out. Variables are described using the arithmetic mean, standard deviations, and frequencies. Chi-square and U Mann-Whitney tests were used. Correlation analysis was performed between neuropsychological characteristics and the degree of affection by tractography (FA and MD). Results: Significant differences were found between the groups of AD versus mixed dementia in FA: right cerebral peduncle 0.5733 versus 0.5557 (p < 0.05), left cerebral peduncle 0.5744 versus 0.5476 (p < 0.01), right external capsule 0.3619 versus 0.3346 (p < 0.01), and left cingulum gyrus 0.4049 versus 0.3756 (p < 0.05). MD: right thalamic posterior radiation 0.0016 versus 0.0010 (p < 0.03) and left external capsule 0.0015 versus 0.0012 (p < 0.03). Conclusion: Using tractography, it is possible to quantify the extent of damage to the white matter tracts (vascular and neurodegenerative). pubtype: Academic Journal doctype: Article src: R language: English refInfo: copyright: @attributes: flag: Y custom: Copyright of Revista Mexicana de Neurociencia is the property of Academia Mexicana de Neurologia and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. item: Revista Mexicana de Neurociencia holder: Academia Mexicana de Neurologia dt: @attributes: year: 2021 holdings: @attributes: islocal: N |
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