Re-evaluation of Sentinel Lymph Node Biopsy for Melanoma.
Opinion Statement: The vast majority of patients newly diagnosed with melanoma present with clinically localized disease, and sentinel lymph node biopsy (SLNB) is a standard of care in the management of these patients, particularly in intermediate thickness cases, in order to provide important progn...
| Publicado en: | Current Treatment Options in Oncology Vol. 22; no. 3; pp. 1 - 20 |
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| Autores principales: | , |
| Formato: | research Journal Article |
| Publicado: |
Springer Nature
Mar2021
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=149470587&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 149470587 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 15272729 3KHC jtl: Current Treatment Options in Oncology issn: 15272729 maglogo: N pubinfo: dt: Mar2021 vid: 22 iid: 3 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 149470587 149470587 NLM33560505 149470587 10.1007/s11864-021-00819-2 NLM33560505 149470587 ppf: 1 ppct: 19 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Re-evaluation of Sentinel Lymph Node Biopsy for Melanoma. aug: au: Morrison, Steven Han, Dale affil: Division of Surgical Oncology, Oregon Health & Science University, 3181 SW Sam Jackson Park Road, 97239, Portland, OR, USA sug: subj: Melanoma Diagnosis Sentinel Lymph Node Biopsy Standards Sentinel Lymph Node Biopsy Methods Melanoma Etiology Neoplasm Metastasis Reproducibility of Results Melanoma Therapy Prognosis Human Neoplasm Staging Algorithms Disease Management Melanoma Mortality Sensitivity and Specificity Scales ab: Opinion Statement: The vast majority of patients newly diagnosed with melanoma present with clinically localized disease, and sentinel lymph node biopsy (SLNB) is a standard of care in the management of these patients, particularly in intermediate thickness cases, in order to provide important prognostic data. However, SLNB also has an important role in the management of patients with other subtypes of melanoma such as thick melanomas, certain thin melanomas, and specific histologic variants of melanoma such as desmoplastic melanoma. Furthermore, there have been technical advances in the SLNB technique, such as the development of newer radiotracers and use of SPECT/CT, and there is some data to suggest performing a SLNB may be therapeutic. Finally, the management of patients with a positive sentinel lymph node (SLN) has undergone dramatic changes over the past several years based on the results of recent important clinical trials. Treatment options for patients with SLN metastases now include surveillance, completion lymph node dissection, and adjuvant therapy with checkpoint inhibitors and targeted therapy. SLNB continues to play a crucial role in the management of patients with melanoma, allowing for risk stratification, potential regional disease control, and further treatment options for patients with a positive SLN. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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