Neural Mechanisms of Human Decision-Making.

We present a theory and neural network model of the neural mechanisms underlying human decision-making. We propose a detailed model of the interaction between brain regions, under a proposer-predictor-actor-critic​ ​framework. This theory is based on detailed animal data and theories of action-selec...

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Published in:Cognitive, Affective & Behavioral Neuroscience Vol. 21; no. 1; pp. 35 - 58
Main Authors: Herd, Seth, Krueger, Kai, Nair, Ananta, Mollick, Jessica, O'Reilly, Randall
Format: Journal Article
Published: Springer Nature Feb2021
Online Access:View this record in EBSCOhost
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      dt: Feb2021
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      pub: Springer Nature
      place: New York, New York
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        10.3758/s13415-020-00842-0
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        atl: Neural Mechanisms of Human Decision-Making.
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          Herd, Seth
          Krueger, Kai
          Nair, Ananta
          Mollick, Jessica
          O'Reilly, Randall
        affil: eCortex, Inc., Boulder, CO, USA
      sug:
      ab: We present a theory and neural network model of the neural mechanisms underlying human decision-making. We propose a detailed model of the interaction between brain regions, under a proposer-predictor-actor-critic​ ​framework. This theory is based on detailed animal data and theories of action-selection. Those theories are adapted to serial operation to bridge levels of analysis and explain human decision-making. Task-relevant areas of cortex propose a candidate plan using fast, model-free, parallel neural computations. Other areas of cortex and medial temporal lobe can then predict​ likely outcomes of that plan in this situation. This optional prediction- (or model-) based computation can produce better accuracy and generalization, at the expense of speed. Next, linked regions of basal ganglia act​ to accept or reject the proposed plan based on its reward history in similar contexts. If that plan is rejected, the process repeats to consider a new option. The reward-prediction system acts as a critic​ to determine the value of the outcome relative to expectations and produce dopamine as a training signal for cortex and basal ganglia. By operating sequentially and hierarchically, the same mechanisms previously proposed for animal action-selection could explain the most complex human plans and decisions. We discuss explanations of model-based decisions, habitization, and risky behavior based on the computational model.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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