18F-FDG-PET/CT Whole-Body Imaging Lung Tumor Diagnostic Model: An Ensemble E-ResNet-NRC with Divided Sample Space.

Under the background of 18F-FDG-PET/CT multimodal whole-body imaging for lung tumor diagnosis, for the problems of network degradation and high dimension features during convolutional neural network (CNN) training, beginning with the perspective of dividing sample space, an E-ResNet-NRC (ensemble Re...

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Publicado en:BioMed Research International pp. 1 - 14
Autores principales: Tao, Zhou, Bing-qiang, Huo, Huiling, Lu, Hongbin, Shi, Pengfei, Yang, Hongsheng, Ding
Formato: diagnostic images equations & formulas pictorial research tables/charts Journal Article
Publicado: Wiley-Blackwell 4/1/2021
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 4/1/2021
      pid: 480
      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1155/2021/8865237
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        atl: 18F-FDG-PET/CT Whole-Body Imaging Lung Tumor Diagnostic Model: An Ensemble E-ResNet-NRC with Divided Sample Space.
      aug:
        au:
          Tao, Zhou
          Bing-qiang, Huo
          Huiling, Lu
          Hongbin, Shi
          Pengfei, Yang
          Hongsheng, Ding
        affil: School of Computer Science and Engineering, North Minzu University, Yinchuan 750021, China
      sug:
        subj:
          Fludeoxyglucose F 18 Pharmacokinetics
          Tomography, Emission-Computed Methods
          Radiopharmaceuticals Diagnostic Use
          Lung Neoplasms Diagnosis
          Diagnostic Imaging
          Neural Networks (Computer) Methods
          Human
          Algorithms
          Descriptive Statistics
          Comparative Studies
          Experimental Studies
          Sensitivity and Specificity
      ab: Under the background of 18F-FDG-PET/CT multimodal whole-body imaging for lung tumor diagnosis, for the problems of network degradation and high dimension features during convolutional neural network (CNN) training, beginning with the perspective of dividing sample space, an E-ResNet-NRC (ensemble ResNet nonnegative representation classifier) model is proposed in this paper. The model includes the following steps: (1) Parameters of a pretrained ResNet model are initialized using transfer learning. (2) Samples are divided into three different sample spaces (CT, PET, and PET/CT) based on the differences in multimodal medical images PET/CT, and ROI of the lesion was extracted. (3) The ResNet neural network was used to extract ROI features and obtain feature vectors. (4) Individual classifier ResNet-NRC was constructed with nonnegative representation NRC at a fully connected layer. (5) Ensemble classifier E-ResNet-NRC was constructed using the "relative majority voting method." Finally, two network models, AlexNet and ResNet-50, and three classification algorithms, nearest neighbor classification algorithm (NNC), softmax, and nonnegative representation classification algorithm (NRC), were combined to compare with the E-ResNet-NRC model in this paper. The experimental results show that the overall classification performance of the Ensemble E-ResNet-NRC model is better than the individual ResNet-NRC, and specificity and sensitivity are more higher; the E-ResNet-NRC has better robustness and generalization ability.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        equations & formulas
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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