Toward a global and reproducible science for brain imaging in neurotrauma: the ENIGMA adult moderate/severe traumatic brain injury working group.

The global burden of mortality and morbidity caused by traumatic brain injury (TBI) is significant, and the heterogeneity of TBI patients and the relatively small sample sizes of most current neuroimaging studies is a major challenge for scientific advances and clinical translation. The ENIGMA (Enha...

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Publicado en:Brain Imaging & Behavior Vol. 15; no. 2; pp. 526 - 555
Autores principales: Olsen, Alexander, Babikian, Talin, Bigler, Erin D., Caeyenberghs, Karen, Conde, Virginia, Dams-O'Connor, Kristen, Dobryakova, Ekaterina, Genova, Helen, Grafman, Jordan, Håberg, Asta K., Heggland, Ingrid, Hellstrøm, Torgeir, Hodges, Cooper B., Irimia, Andrei, Jha, Ruchira M., Johnson, Paula K., Koliatsos, Vassilis E., Levin, Harvey, Li, Lucia M., Lindsey, Hannah M.
Formato: meta analysis research Journal Article
Publicado: Springer Nature Apr2021
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Springer Nature
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        atl: Toward a global and reproducible science for brain imaging in neurotrauma: the ENIGMA adult moderate/severe traumatic brain injury working group.
      aug:
        au:
          Olsen, Alexander
          Babikian, Talin
          Bigler, Erin D.
          Caeyenberghs, Karen
          Conde, Virginia
          Dams-O'Connor, Kristen
          Dobryakova, Ekaterina
          Genova, Helen
          Grafman, Jordan
          Håberg, Asta K.
          Heggland, Ingrid
          Hellstrøm, Torgeir
          Hodges, Cooper B.
          Irimia, Andrei
          Jha, Ruchira M.
          Johnson, Paula K.
          Koliatsos, Vassilis E.
          Levin, Harvey
          Li, Lucia M.
          Lindsey, Hannah M.
        affil: Department of Psychology, Norwegian University of Science and Technology, 7491, Trondheim, Norway
      sug:
        subj:
          Magnetic Resonance Imaging
          Reproducibility of Results
          Human
          Brain
          Neuroradiography
          Adult
          Comparative Studies
          Meta Analysis
          Multicenter Studies
          Evaluation Research
          Validation Studies
          Short Portable Mental Status Questionnaire
          Clinical Assessment Tools
          Scales
          Arthritis Impact Measurement Scales
          Adult: 19-44 years
      ab: The global burden of mortality and morbidity caused by traumatic brain injury (TBI) is significant, and the heterogeneity of TBI patients and the relatively small sample sizes of most current neuroimaging studies is a major challenge for scientific advances and clinical translation. The ENIGMA (Enhancing NeuroImaging Genetics through Meta-Analysis) Adult moderate/severe TBI (AMS-TBI) working group aims to be a driving force for new discoveries in AMS-TBI by providing researchers world-wide with an effective framework and platform for large-scale cross-border collaboration and data sharing. Based on the principles of transparency, rigor, reproducibility and collaboration, we will facilitate the development and dissemination of multiscale and big data analysis pipelines for harmonized analyses in AMS-TBI using structural and functional neuroimaging in combination with non-imaging biomarkers, genetics, as well as clinical and behavioral measures. Ultimately, we will offer investigators an unprecedented opportunity to test important hypotheses about recovery and morbidity in AMS-TBI by taking advantage of our robust methods for large-scale neuroimaging data analysis. In this consensus statement we outline the working group's short-term, intermediate, and long-term goals.
      pubtype: Academic Journal
      doctype:
        meta analysis
        research
        Journal Article
      ougenre: Article
    language: English
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