The clinical utility of proton magnetic resonance spectroscopy in traumatic brain injury: recommendations from the ENIGMA MRS working group.
Proton (1H) magnetic resonance spectroscopy provides a non-invasive and quantitative measure of brain metabolites. Traumatic brain injury impacts cerebral metabolism and a number of research groups have successfully used this technique as a biomarker of injury and/or outcome in both pediatric and ad...
| Publicado en: | Brain Imaging & Behavior Vol. 15; no. 2; pp. 504 - 526 |
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| Autores principales: | , , , , , , , , , , , |
| Formato: | Journal Article |
| Publicado: |
Springer Nature
Apr2021
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=149713797&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 149713797 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 19317557 3GSC jtl: Brain Imaging & Behavior issn: 19317557 maglogo: N pubinfo: dt: Apr2021 vid: 15 iid: 2 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 149713797 149713797 NLM32797399 10.1007/s11682-020-00330-6 NLM32797399 149713797 ppf: 504 ppct: 22 formats: fmt: @attributes: type: P tig: atl: The clinical utility of proton magnetic resonance spectroscopy in traumatic brain injury: recommendations from the ENIGMA MRS working group. aug: au: Bartnik-Olson, Brenda L Alger, Jeffry R Babikian, Talin Harris, Ashley D Holshouser, Barbara Kirov, Ivan I Maudsley, Andrew A Thompson, Paul M Dennis, Emily L Tate, David F Wilde, Elisabeth A Lin, Alexander affil: Department of Radiology, Loma Linda University Medical Center, Loma Linda, CA, USA sug: subj: Magnetic Resonance Imaging Child Brain Adult Proton Magnetic Resonance Spectroscopy Magnetic Resonance Spectroscopy Clinical Assessment Tools Scales Child: 6-12 years Adult: 19-44 years ab: Proton (1H) magnetic resonance spectroscopy provides a non-invasive and quantitative measure of brain metabolites. Traumatic brain injury impacts cerebral metabolism and a number of research groups have successfully used this technique as a biomarker of injury and/or outcome in both pediatric and adult TBI populations. However, this technique is underutilized, with studies being performed primarily at centers with access to MR research support. In this paper we present a technical introduction to the acquisition and analysis of in vivo 1H magnetic resonance spectroscopy and review 1H magnetic resonance spectroscopy findings in different injury populations. In addition, we propose a basic 1H magnetic resonance spectroscopy data acquisition scheme (Supplemental Information) that can be added to any imaging protocol, regardless of clinical magnetic resonance platform. We outline a number of considerations for study design as a way of encouraging the use of 1H magnetic resonance spectroscopy in the study of traumatic brain injury, as well as recommendations to improve data harmonization across groups already using this technique. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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