Potentially inappropriate prescribing in older hospitalized Dutch patients according to the STOPP/START criteria v2: a longitudinal study.
Purpose: To investigate prevalence, independent associations, and variation over time of potentially inappropriate prescriptions in a population of older hospitalized patients. Methods: A longitudinal study using a large dataset of hospital admissions of older patients (≥ 70 years) based on an elect...
| Publicado en: | European Journal of Clinical Pharmacology Vol. 77; no. 5; pp. 777 - 786 |
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| Autores principales: | , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Springer Nature
May2021
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=149714823&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 149714823 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00316970 NP9 jtl: European Journal of Clinical Pharmacology issn: 00316970 maglogo: N pubinfo: dt: May2021 vid: 77 iid: 5 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 149714823 147391205 149714823 149714823 10.1007/s00228-020-03052-2 149714823 ppf: 777 ppct: 9 formats: fmt: @attributes: type: P tig: atl: Potentially inappropriate prescribing in older hospitalized Dutch patients according to the STOPP/START criteria v2: a longitudinal study. aug: au: Damoiseaux-Volman, Birgit A. Medlock, Stephanie Raven, Kimmy Sent, Danielle Romijn, Johannes A. van der Velde, Nathalie Abu-Hanna, Ameen affil: Amsterdam UMC, Department of Medical Informatics, Amsterdam Public Health Research Institute, University of Amsterdam, Meibergdreef 9, Amsterdam, The Netherlands sug: subj: Inappropriate Prescribing Epidemiology Inappropriate Prescribing Trends Hospitalization of Older Persons Human Netherlands Prospective Studies Aged Aged, 80 and Over Multiple Logistic Regression Descriptive Statistics Clinical Assessment Tools Length of Stay Polypharmacy Odds Ratio Inpatients Aged: 65+ years Aged, 80 & over ab: Purpose: To investigate prevalence, independent associations, and variation over time of potentially inappropriate prescriptions in a population of older hospitalized patients. Methods: A longitudinal study using a large dataset of hospital admissions of older patients (≥ 70 years) based on an electronic health records cohort including data from 2015 to 2019. Potentially inappropriate medication (PIM) and potential prescribing omission (PPO) prevalence during hospital stay were identified based on the Dutch STOPP/START criteria v2. Univariate and multivariate logistic regression were used for analyzing associations and trends over time. Results: The data included 16,687 admissions. Of all admissions, 56% had ≥ 1 PIM and 58% had ≥ 1 PPO. Gender, age, number of medications, number of diagnoses, Charlson score, and length of stay were independently associated with both PIMs and PPOs. Additionally, number of departments and number of prescribing specialties were independently associated with PIMs. Over the years, the PIM prevalence did not change (OR = 1.00, p =.95), whereas PPO prevalence increased (OR = 1.08, p <.001). However, when corrected for changes in patient characteristics such as number of diagnoses, the PIM (aOR = 0.91, p <.001) and PPO prevalence (aOR = 0.94, p <.001) decreased over the years. Conclusion: We found potentially inappropriate prescriptions in the majority of admissions of older patients. Prescribing relatively improved over time when considering complexity of the admissions. Nevertheless, the high prevalence shows a clear need to better address this issue in clinical practice. Studies seeking effective (re)prescribing interventions are warranted. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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