A happiness magnet? Reviewing the evidence for repetitive transcranial magnetic stimulation in major depressive disorder.

Objectives: First, to conduct a historical review of the evidence for repetitive transcranial magnetic stimulation (rTMS) for major depressive disorder and determine a clinical algorithm. Second, to identify opportunities for research.Methods: Literature searches were conducted of the MEDLINE databa...

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Publicado en:Australasian Psychiatry Vol. 29; no. 2; pp. 207 - 214
Autores principales: Pridmore, William, Pridmore, Saxby
Formato: Journal Article
Publicado: Sage Publications Inc. Apr2021
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Apr2021
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      pub: Sage Publications Inc.
      place: Thousand Oaks, California
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        atl: A happiness magnet? Reviewing the evidence for repetitive transcranial magnetic stimulation in major depressive disorder.
      aug:
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          Pridmore, William
          Pridmore, Saxby
        affil: Launceston General Hospital, Tasmanian Health Service, Tasmania
      sug:
        subj:
          Depression Therapy
          Happiness
          Australia
          Transcranial Magnetic Stimulation
          Treatment Outcomes
          Magnets
          Scales
      ab: Objectives: First, to conduct a historical review of the evidence for repetitive transcranial magnetic stimulation (rTMS) for major depressive disorder and determine a clinical algorithm. Second, to identify opportunities for research.Methods: Literature searches were conducted of the MEDLINE database, UpToDate and the Australian National University Library SuperSearch from 1 January 2000 to 30 September 2019. The search terms used were 'transcranial magnetic stimulation', 'major depressive disorder' and 'depression'.Results: There were 24 meta-analyses identified, demonstrating a clear clinical effect. Left high-frequency rTMS had the most evidence. Ideal clinical parameters and study design were explored.Conclusion: Use of rTMS for some patients with depression is justified. Open research questions include the comparative efficacy of right low-frequency and bilateral stimulation, the role of rTMS in medication-naïve patients, and maintenance of effect.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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