Inducibility of atrial fibrillation after catheter ablation predicts recurrences of atrial fibrillation: a meta‐analysis.
Background: Pulmonary vein isolation (PVI) is a component of standard care for patients with symptomatic atrial fibrillation (AF). Procedural inducibility of AF following PVI has been suggested as predictor of AF recurrence but is discussed controversially. This meta‐analysis aimed at evaluating the...
| Publicado en: | Pacing & Clinical Electrophysiology Vol. 44; no. 4; pp. 667 - 677 |
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| Autores principales: | , , , , , , |
| Formato: | research systematic review tables/charts Journal Article |
| Publicado: |
Wiley-Blackwell
Apr2021
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=149757169&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 149757169 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 01478389 4F8 jtl: Pacing & Clinical Electrophysiology issn: 01478389 maglogo: Y pubinfo: dt: Apr2021 vid: 44 iid: 4 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 149757169 149305170 149757169 149757169 10.1111/pace.14216 149757169 ppf: 667 ppct: 10 formats: fmt: – @attributes: type: T – @attributes: type: C – @attributes: type: P tig: atl: Inducibility of atrial fibrillation after catheter ablation predicts recurrences of atrial fibrillation: a meta‐analysis. aug: au: Millenaar, Dominic Becker, Nicolas Pavlicek, Valérie Wintrich, Jan Böhm, Michael Mahfoud, Felix Ukena, Christian affil: Department of Internal Medicine III, Cardiology, Angiology and Intensive Care Medicine, Saarland University Hospital, Homburg/Saar, Germany sug: subj: Pulmonary Veins Surgery Catheter Ablation Methods Atrial Fibrillation Surgery Recurrence Human Systematic Review Meta Analysis Electrophysiology Medline Odds Ratio Confidence Intervals Male Female Heart Conduction System Physiopathology Isoproterenol Male Female ab: Background: Pulmonary vein isolation (PVI) is a component of standard care for patients with symptomatic atrial fibrillation (AF). Procedural inducibility of AF following PVI has been suggested as predictor of AF recurrence but is discussed controversially. This meta‐analysis aimed at evaluating the relevance of electrophysiological inducibility of AF following PVI for future AF recurrences. Methods: A literature search of MEDLINE and Web of Science was performed until April 2020. Prospective trials of PVI in patients with AF and post‐procedural atrial stimulation to test for inducibility of AF as well as adequate follow‐up for AF recurrence (defined as AF >10 s to >10 min at follow‐up) were included. Odds ratios (ORs) were analyzed using random‐effects models. Results: A total of 11 trials with 1544 patients (follow‐up 7–39 months, age 56 ± 6 years, predominantly male 74 ± 6%) were included. Inducibility of AF post‐PVI was predictive for AF recurrence during follow‐up (OR 2.08; 95% CI 1.25 to 3.46). Prediction for AF recurrence at follow‐up was better for patients with paroxysmal AF (OR 4.06; 95% CI 1.39 to 11.91), stimulation in the CS (OR 2.82, 95% CI 1.17 to 6.79). A trend towards higher ORs was seen without the use of isoproterenol (OR 2.43; 95% CI 1.17 to 5.07), as well as few stimulations during induction and a short definition of AF in meta‐regression analyses. Conclusions: Electrophysiological inducibility of AF following PVI was predictive for future recurrence of AF, in particular in patients with paroxysmal AF, stimulation in only CS and no use of isoproterenol. pubtype: Academic Journal doctype: meta analysis research systematic review tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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