Preclinical evaluation of 5-methyltetrahydrofolate-based radioconjugates—new perspectives for folate receptor–targeted radionuclide therapy.

Purpose: The folate receptor (FR) is frequently overexpressed in a variety of tumor types and, hence, an interesting target for radionuclide therapy. The aim of this study was to evaluate a new class of albumin-binding radioconjugates comprising 5-methyltetrahydrofolate (5-MTHF) as a targeting agent...

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Bibliographic Details

Published in:	European Journal of Nuclear Medicine & Molecular Imaging Vol. 48; no. 4; pp. 972 - 984
Main Authors:	Guzik, Patrycja, Benešová, Martina, Ratz, Magdalena, Monné Rodríguez, Josep M., Deberle, Luisa M., Schibli, Roger, Müller, Cristina
Format:	Journal Article
Published:	Springer Nature Apr2021
Online Access:	View this record in EBSCOhost