MRI-guided breast biopsy based on diffusion-weighted imaging: a feasibility study.

Objectives: This study evaluated the feasibility of DWI for lesion targeting in MRI-guided breast biopsies. Furthermore, it assessed device positioning on DWI during biopsy procedures.Methods: A total of 87 biopsy procedures (5/87 bilateral) consecutively performed between March 2019 and June 2020 w...

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Publicado en:European Radiology Vol. 31; no. 5; pp. 2645 - 2657
Autores principales: Montemezzi, Stefania, Cardano, Giuseppe, Storer, Silvia, Cardobi, Nicolò, Cavedon, Carlo, Camera, Lucia
Formato: diagnostic images research tables/charts Journal Article
Publicado: Springer Nature May2021
Acceso en línea:Ver este registro en EBSCOhost
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      dt: May2021
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s00330-020-07396-2
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        atl: MRI-guided breast biopsy based on diffusion-weighted imaging: a feasibility study.
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        au:
          Montemezzi, Stefania
          Cardano, Giuseppe
          Storer, Silvia
          Cardobi, Nicolò
          Cavedon, Carlo
          Camera, Lucia
        affil: Radiology Unit, Department of Pathology and Diagnostics, Azienda Ospedaliera Universitaria Integrata – Verona, P.le Stefani 1, 37126, Verona, Italy
      sug:
        subj:
          Magnetic Resonance Imaging
          Breast Neoplasms
          Contrast Media
          Biopsy
          Retrospective Design
          Sensitivity and Specificity
          Pilot Studies
          Breast
          Human
      ab: Objectives: This study evaluated the feasibility of DWI for lesion targeting in MRI-guided breast biopsies. Furthermore, it assessed device positioning on DWI during biopsy procedures.Methods: A total of 87 biopsy procedures (5/87 bilateral) consecutively performed between March 2019 and June 2020 were retrospectively reviewed: in these procedures, a preliminary DWI sequence (b = 1300 s/mm2) was acquired to assess lesion detectability. We included 64/87 procedures on lesions detectable at DWI; DWI sequences were added to the standard protocol to localize lesion and biopsy device and to assess the site marker correct positioning.Results: Mass lesions ranged from 5 to 48 mm, with a mean size of 10.7 mm and a median size of 8 mm. Non-mass lesions ranged from 7 to 90 mm, with a mean size of 33.9 mm and a median size of 31 mm. Positioning of the coaxial system was confirmed on both T1-weighted and DWI sequences. At DWI, the biopsy needle was detectable in 62/64 (96.9%) cases; it was not visible in 2/64 (3.1%) cases. The site marker was always identified using T1-weighted imaging; a final DWI sequence was acquired in 44/64 cases (68.8%). In 42/44 cases (95.5%), the marker was recognizable at DWI.Conclusions: DWI can be used as a cost-effective, highly reliable technique for targeting both mass and non-mass lesions, with a minimum size of 5 mm, detectable at pre-procedural DWI. DWI is also a feasible technique to localize the biopsy device and to confirm the deployment of the site marker.Key Points: • MRI-guided breast biopsy is performed in referral centers by an expert dedicated staff, based on prior MR imaging; contrast agent administration is usually needed for lesion targeting. • DWI represents a feasible, highly reliable technique for lesion targeting, avoiding contrast agent administration. • DWI allows a precise localization of both biopsy needle device and site marker.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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