Texture analysis using T1-weighted images for muscles in Charcot-Marie-Tooth disease patients and volunteers.
Objectives: To explore whether texture features using T1-weighted images correlate with fat fraction, and whether they differ between Charcot-Marie-Tooth (CMT) disease patients and volunteers.Methods: The institutional review board approved this retrospective study, and the requirement for informed...
| Publicado en: | European Radiology Vol. 31; no. 5; pp. 3508 - 3518 |
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| Autores principales: | , , , , |
| Formato: | diagnostic images research tables/charts Journal Article |
| Publicado: |
Springer Nature
May2021
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=149789362&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 149789362 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09387994 NPH jtl: European Radiology issn: 09387994 maglogo: N pubinfo: dt: May2021 vid: 31 iid: 5 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 149789362 149789362 NLM33125561 149789362 10.1007/s00330-020-07435-y NLM33125561 149789362 ppf: 3508 ppct: 10 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Texture analysis using T1-weighted images for muscles in Charcot-Marie-Tooth disease patients and volunteers. aug: au: Lee, Ji Hyun Yoon, Young Cheol Kim, Hyun Su Kim, Jae-Hun Choi, Byung-Ok affil: Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Ilwon-Ro, Gangnam-gu, 06351, Seoul, South Korea sug: subj: Charcot-Marie-Tooth Disease Magnetic Resonance Imaging Research Subjects Retrospective Design Muscles Human ab: Objectives: To explore whether texture features using T1-weighted images correlate with fat fraction, and whether they differ between Charcot-Marie-Tooth (CMT) disease patients and volunteers.Methods: The institutional review board approved this retrospective study, and the requirement for informed consent was waived; data of eighteen CMT patients and eighteen healthy volunteers from a previous study was used. Texture features of the muscles including mean, standard deviation (SD), skewness, kurtosis, and entropy of the signal intensity were derived from T1-weighted images. Spearman's correlation analysis was used to assess the relationship between texture features and fat fraction measured by 3D multiple gradient echo Dixon-based sequence. Mann-Whitney U test was used to compare the texture features between CMT patients and volunteers. Intraobserver and interobserver agreements for the texture features were assessed using the intraclass correlation coefficient.Results: The SD (ρ = 0.256, p < 0.001) and entropy (ρ = 0.263, p < 0.001) were significantly and positively correlated with fat fraction; skewness (ρ = - 0.110, p = 0.027) and kurtosis (ρ = - 0.149, p = 0.003) were significantly and inversely correlated with fat fraction. The CMT patients showed a significantly higher SD (63.45 vs. 49.26; p < 0.001), skewness (1.06 vs. 0.56; p < 0.001), kurtosis (4.00 vs. 1.81; p < 0.001), and entropy (3.20 vs. 3.02; p < 0.001) than did the volunteers. Intraobserver and interobserver agreements were almost perfect for mean, SD, and entropy.Conclusions: Texture features using T1-weighted images correlated with fat fraction and differed between CMT patients and volunteers.Key Points: • Standard deviation and entropy of muscles derived from T1-weighted images were significantly and positively correlated with the muscle fat fraction. • Mean, standard deviation, and entropy were considered highly reliable in muscle analyses. • Texture features may have the potential to diagnose early stage of intramuscular fatty infiltration. pubtype: Academic Journal doctype: diagnostic images research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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