Assessing glaucoma deterioration using Spaeth/Richman contrast sensitivity test.

Purpose: To assess changes in the central and peripheral contrast sensitivity in severe primary open-angle glaucoma (POAG) patients using a computer-based Spaeth/Richman contrast sensitivity test (SPARCS) over a period of 24 months. Methods: Our pilot, observational study included 15 patients (30 ey...

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Publicado en:Therapeutic Advances in Ophthalmology Vol. 12; pp. 1 - 9
Autores principales: Ichhpujani, Parul, Singh, Tanu, Thakur, Sahil, Singh, Rohan Bir, Kumar, Suresh
Formato: research tables/charts Journal Article
Publicado: Sage Publications Inc. Jan-Dec2020
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jan-Dec2020
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      pub: Sage Publications Inc.
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        atl: Assessing glaucoma deterioration using Spaeth/Richman contrast sensitivity test.
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          Ichhpujani, Parul
          Singh, Tanu
          Thakur, Sahil
          Singh, Rohan Bir
          Kumar, Suresh
        affil: Professor, Department of Ophthalmology, Government Medical College & Hospital, Sector-32, Chandigarh 160030, India
      sug:
        subj:
          Glaucoma Diagnosis
          Glaucoma Physiopathology
          Vision Tests Methods
          Human
          Female
          Male
          Middle Age
          Aged
          Pilot Studies
          Nonexperimental Studies
          Visual Acuity
          Intraocular Pressure
          Visual Fields
          Time Factors
          Descriptive Statistics
          Spearman's Rank Correlation Coefficient
          Correlation Coefficient
          Outcome Assessment
          Middle Aged: 45-64 years
          Aged: 65+ years
          Female
          Male
      ab: Purpose: To assess changes in the central and peripheral contrast sensitivity in severe primary open-angle glaucoma (POAG) patients using a computer-based Spaeth/Richman contrast sensitivity test (SPARCS) over a period of 24 months. Methods: Our pilot, observational study included 15 patients (30 eyes) with severe POAG. Visual acuity, intraocular pressure, number of anti-glaucoma drugs, visual fields, and SPARCS score were recorded at first visit and at 12 and 24 months. Results: We observed changes in mean deviation (MD) from -19.37 ± 5.04 to -20.63 ± 4.07, mean pattern standard deviation (PSD) from 11.49 ± 2.61 to 11.35 ± 2.01, and mean SPARCS score from 54.97 ± 15.66 to 53.50 ± 16.42. We found no statistically significant difference between visual field parameters and SPARCS scores associated with the number or type of prescribed anti-glaucoma drugs. Spearman's correlation coefficient of SPARCS at baseline (SPARCS1) versus MD at baseline (MD1) was 0.274 (p = 0.142) and SPARCS1 versus PSD at baseline (PSD1) was -0.163 (p = 0.389). The correlation coefficient between SPARCS at 12 months (SPARCS2) versus MD (MD2) at the same time point was computed to be 0.391 (p = 0.03), whereas SPARCS2 versus PSD at 12 months was -0.212 (p = 0.262). Similarly, we found the coefficient to be 0.336 (p = 0.069) for SPARCS3 (SPARCS at 24 months) versus MD3 (MD at 24 months) and -0.242 (p = 0.197) for SPARCS3 versus PSD3 (PSD at 24 months). Correlation coefficients between SPARCS1/2, SPARCS1/3, MD1/2, MD1/3 PSD1/2, and PSD1/3 were 0.856, 0.865, 0.748, 0.722, 0.497, and 0.562, respectively (p < 0.001). MD changed by 9.46% ± 12.73%, PSD by 0.64% ± 14.03%, and average SPARCS by 3.31% ± 12.73% over 24 months. Conclusion: The data from our study indicate the utilitarian application of SPARCS, an inexpensive and readily available tool for monitoring functional deterioration in cases with advanced glaucomatous damage, especially in resource-poor settings. Furthermore, it is a useful and reliable alternative to the imaging modalities where retinal nerve fiber layer measurement can be erroneous in advanced cases secondary to the floor effect.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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