Simultaneous Identification of Cell of Origin, Translocations, and Hotspot Mutations in Diffuse Large B-Cell Lymphoma Using a Single RNA-Sequencing Assay.

Objectives: Diffuse large B-cell lymphoma (DLBCL) is an aggressive non-Hodgkin lymphoma with a heterogenous genetic landscape that can require multiple assays to characterize. We reviewed a 1-step RNA-based assay to determine cell of origin (COO), detect translocations, and identify mutations and to...

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Publicado en:	American Journal of Clinical Pathology Vol. 155; no. 5; pp. 748 - 755
Autores principales:	Crotty, Rory, Hu, Krista, Stevenson, Kristen, Pontius, Maggie Y, Sohani, Aliyah R, Ryan, Russell J H, Rueckert, Erroll, Brauer, Heather A, Hudson, Briana, Berlin, Aaron M, Rodenbaugh, Matt, Licon, Abel, Haimes, Josh, Iafrate, A John, Nardi, Valentina, Louissaint, Abner
Formato:	Journal Article
Publicado:	Oxford University Press / USA May2021
Acceso en línea:	Ver este registro en EBSCOhost