Rapid Validation of Whole-Slide Imaging for Primary Histopathology Diagnosis.
Objectives: The ongoing global severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic necessitates adaptations in the practice of surgical pathology at scale. Primary diagnosis by whole-slide imaging (WSI) is a key component that would aid departments in providing uninterrupted histop...
| Publicado en: | American Journal of Clinical Pathology Vol. 155; no. 5; pp. 638 - 649 |
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| Autores principales: | , , , , , , , , , |
| Formato: | Journal Article |
| Publicado: |
Oxford University Press / USA
May2021
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=150005083&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 150005083 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00029173 2RW jtl: American Journal of Clinical Pathology issn: 00029173 maglogo: N pubinfo: dt: May2021 vid: 155 iid: 5 pid: 10398 pub: Oxford University Press / USA artinfo: ui: 150005083 150005083 NLM33511392 10.1093/ajcp/aqaa280 NLM33511392 150005083 ppf: 638 ppct: 11 formats: tig: atl: Rapid Validation of Whole-Slide Imaging for Primary Histopathology Diagnosis. aug: au: Samuelson, Megan I Chen, Stephanie J Boukhar, Sarag A Schnieders, Eric M Walhof, Mackenzie L Bellizzi, Andrew M Robinson, Robert A D, Anand Rajan K Rajan Kd, Anand Rajan K D, Anand affil: Department of Pathology, University of Iowa Hospitals and Clinics, University of Iowa , Iowa City, IA, USA sug: ab: Objectives: The ongoing global severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic necessitates adaptations in the practice of surgical pathology at scale. Primary diagnosis by whole-slide imaging (WSI) is a key component that would aid departments in providing uninterrupted histopathology diagnosis and maintaining revenue streams from disruption. We sought to perform rapid validation of the use of WSI in primary diagnosis meeting recommendations of the College of American Pathologists guidelines.Methods: Glass slides from clinically reported cases from 5 participating pathologists with a preset washout period were digitally scanned and reviewed in settings identical to typical reporting. Cases were classified as concordant or with minor or major disagreement with the original diagnosis. Randomized subsampling was performed, and mean concordance rates were calculated.Results: In total, 171 cases were included and distributed equally among participants. For the group as a whole, the mean concordance rate in sampled cases (n = 90) was 83.6% counting all discrepancies and 94.6% counting only major disagreements. The mean pathologist concordance rate in sampled cases (n = 18) ranged from 90.49% to 97%.Conclusions: We describe a novel double-blinded method for rapid validation of WSI for primary diagnosis. Our findings highlight the occurrence of a range of diagnostic reproducibility when deploying digital methods. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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