Trends in post–heart transplant biopsies for graft rejection versus nonrejection.

With alternatives such as gene profiling available for surveillance after orthotopic heart transplantation, we sought to evaluate the utilization of endomyocardial biopsies (EMBs) for hospitalized patients after heart transplantation. Surveillance EMBs in patients with and without complications were...

Descripción completa

Detalles Bibliográficos
Publicado en:Baylor University Medical Center Proceedings Vol. 34; no. 3; pp. 345 - 349
Autores principales: Jamil, Aayla K., Afzal, Aasim, Nisar, Tariq, Kluger, Aaron Y., Felius, Joost, Wencker, Detlef, Hall, Shelley A., Kale, Parag
Formato: research tables/charts Journal Article
Publicado: Taylor & Francis Ltd Jul2021
Acceso en línea:Ver este registro en EBSCOhost
fields @attributes:
  recordID: 1
pdfLink:
plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=150005636&site=ehost-live
header:
  @attributes:
    shortDbName: ccm
    uiTerm: 150005636
    longDbName: CINAHL Complete
    uiTag: AN
  controlInfo:
    bkinfo:
    dissinfo:
    jinfo:
      jid:
        08998280
        1XEP
      jtl: Baylor University Medical Center Proceedings
      issn: 08998280
      maglogo: N
    pubinfo:
      dt: Jul2021
      vid: 34
      iid: 3
      pid: 377
      pub: Taylor & Francis Ltd
      place: Philadelphia, Pennsylvania
    artinfo:
      ui:
        150005636
        148351753
        150005636
        150005636
        10.1080/08998280.2021.1873032
        150005636
      ppf: 345
      ppct: 4
      formats:
        fmt:
          @attributes:
            type: P
      tig:
        atl: Trends in post–heart transplant biopsies for graft rejection versus nonrejection.
      aug:
        au:
          Jamil, Aayla K.
          Afzal, Aasim
          Nisar, Tariq
          Kluger, Aaron Y.
          Felius, Joost
          Wencker, Detlef
          Hall, Shelley A.
          Kale, Parag
        affil: Center for Advanced Heart and Lung Disease, Baylor University Medical Center, Dallas, Texas
      sug:
        subj:
          Heart Transplantation Rehabilitation
          Biopsy Trends
          Graft Rejection
          Human
          Length of Stay
          Surgical Patients
          Descriptive Statistics
          Cost Benefit Analysis
          COVID-19 Pandemic
      ab: With alternatives such as gene profiling available for surveillance after orthotopic heart transplantation, we sought to evaluate the utilization of endomyocardial biopsies (EMBs) for hospitalized patients after heart transplantation. Surveillance EMBs in patients with and without complications were evaluated from the 2004 to 2014 National Inpatient Sample. Over the study period, there was no significant change in the number of EMB procedures performed (P = 0.44). Of 37,955 EMBs, 2283 (6%) were in the setting of graft complications, while 35,672 EMBs were not related to graft complications. EMBs in graft complications did not show a significant increase in length of stay over time (P = 0.06), but had a significant increase in cost over time (P = 0.001). However, those with graft complications had an average of a 5-day longer length of stay (P < 0.001) and costs that were $88,816 (P < 0.001) more expensive compared with those without graft complications. In conclusion, the vast majority of in-hospital EMBs were not related to heart transplantation complications. Nevertheless, EMB hospitalizations with graft complications showed significantly greater length of stay and cost. With the COVID-19 pandemic, it seems more effective to use minimal-contact health surveillance methods rather than invasive EMBs.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
    refInfo:
    holdings:
      @attributes:
        islocal: N