Quantile Regression Forests to Identify Determinants of Neighborhood Stroke Prevalence in 500 Cities in the USA: Implications for Neighborhoods with High Prevalence.

Stroke exerts a massive burden on the US health and economy. Place-based evidence is increasingly recognized as a critical part of stroke management, but identifying the key determinants of neighborhood stroke prevalence and the underlying effect mechanisms is a topic that has been treated sparingly...

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Publicado en:Journal of Urban Health Vol. 98; no. 2; pp. 259 - 271
Autores principales: Hu, Liangyuan, Ji, Jiayi, Li, Yan, Liu, Bian, Zhang, Yiyi
Formato: Artículo
Publicado: Springer Nature Apr2021
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Acceso en línea:Ver este registro en EBSCOhost
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      dt: Apr2021
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      pub: Springer Nature
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        10.1007/s11524-020-00478-y
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        atl: Quantile Regression Forests to Identify Determinants of Neighborhood Stroke Prevalence in 500 Cities in the USA: Implications for Neighborhoods with High Prevalence.
      aug:
        au:
          Hu, Liangyuan
          Ji, Jiayi
          Li, Yan
          Liu, Bian
          Zhang, Yiyi
        affil:
          Department of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, 1425 Madison Avenue, 10029, New York, NY, USA
          Institute for Health Care Delivery Science, Icahn School of Medicine at Mount Sinai, New York, NY, USA
          Department of Obstetrics, Gynecology, and Reproductive Science, Icahn School of Medicine at Mount Sinai, New York, NY, USA
          Division of General Medicine, Columbia University, New York, NY, USA
      su:
        Neighborhoods
        Urban health
        Older people
        Quantile regression
        Machine learning
      sug:
        subj:
          Neighborhoods
          Urban health
          Older people
          Quantile regression
          Machine learning
      keyword:
        Cardiovascular health
        Neighborhood
        Prevention
        Cardiovascular health
        Neighborhood
        Prevention
      ab: Stroke exerts a massive burden on the US health and economy. Place-based evidence is increasingly recognized as a critical part of stroke management, but identifying the key determinants of neighborhood stroke prevalence and the underlying effect mechanisms is a topic that has been treated sparingly in the literature. We aim to fill in the research gaps with a study focusing on urban health. We develop and apply analytical approaches to address two challenges. First, domain expertise on drivers of neighborhood-level stroke outcomes is limited. Second, commonly used linear regression methods may provide incomplete and biased conclusions. We created a new neighborhood health data set at census tract level by pooling information from multiple sources. We developed and applied a machine learning–based quantile regression method to uncover crucial neighborhood characteristics for neighborhood stroke outcomes among vulnerable neighborhoods burdened with high prevalence of stroke. Neighborhoods with a larger share of non-Hispanic blacks, older adults, or people with insufficient sleep tended to have a higher prevalence of stroke, whereas neighborhoods with a higher socio-economic status in terms of income and education had a lower prevalence of stroke. The effects of five major determinants varied geographically and were significantly stronger among neighborhoods with high prevalence of stroke. Highly flexible machine learning identifies true drivers of neighborhood cardiovascular health outcomes from wide-ranging information in an agnostic and reproducible way. The identified major determinants and the effect mechanisms can provide important avenues for prioritizing and allocating resources to develop optimal community-level interventions for stroke prevention.
      pubtype: Academic Journal
      doctype: Article
      src: R
    language: English
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