Neuroplasticity in Corticolimbic Brain Regions in Patients After Anterior Cruciate Ligament Reconstruction.
Context: Fear has been cited as the primary barrier to return to sport (RTS) by athletes after anterior cruciate ligament reconstruction (ACLR). Understanding the neural factors that contribute to fear after ACLR may help us to identify interventions for this population. Objective: To characterize t...
| Publicado en: | Journal of Athletic Training (KnowledgeWorks Global, Ltd) Vol. 56; no. 4; pp. 418 - 427 |
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| Autores principales: | , , , , , |
| Formato: | diagnostic images research tables/charts Journal Article |
| Publicado: |
KnowledgeWorks Global, Ltd
Apr2021
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=150047488&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 150047488 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10626050 HB36 jtl: Journal of Athletic Training (KnowledgeWorks Global, Ltd) issn: 10626050 maglogo: N pubinfo: dt: Apr2021 vid: 56 iid: 4 pid: 81084 pub: KnowledgeWorks Global, Ltd place: Richmond, Virginia artinfo: ui: 150047488 150047488 150047488 10.4085/JAT0042-20 150047488 ppf: 418 ppct: 9 formats: tig: atl: Neuroplasticity in Corticolimbic Brain Regions in Patients After Anterior Cruciate Ligament Reconstruction. aug: au: Baez, Shelby Andersen, Anders Andreatta, Richard Cormier, Marc Gribble, Phillip A. Hoch, Johanna Marie affil: Department of Kinesiology, Michigan State University, East Lansing sug: subj: Anterior Cruciate Ligament Injuries Surgery Anterior Cruciate Ligament Reconstruction Rehabilitation Neuronal Plasticity Evaluation Cerebral Cortex Physiology Limbic System Physiology Athletic Injuries Psychosocial Factors Fear Prevention and Control Task Performance and Analysis Human Matched Case Control Comparative Studies Activities of Daily Living Magnetic Resonance Imaging Methods Neuroradiography Paired T-Tests Athletes Psychosocial Factors Parietal Lobe Thalamus Cerebellum Occipital Lobe Female Questionnaires Imagination Descriptive Statistics Mann-Whitney U Test Exploratory Research Adolescence Adult Data Analysis Software Scales Adolescent: 13-18 years Adult: 19-44 years Female ab: Context: Fear has been cited as the primary barrier to return to sport (RTS) by athletes after anterior cruciate ligament reconstruction (ACLR). Understanding the neural factors that contribute to fear after ACLR may help us to identify interventions for this population. Objective: To characterize the underlying neural substrate of injury-related fear in patients after ACLR versus healthy matched control individuals during a picture imagination task (PIT) consisting of sport-specific images and images of activities of daily living (ADL). Design: Case-control study. Setting: Research laboratory. Patients or Other Participants: A total of 24 right-hand– dominant participants (12 with left-sided ACLR and 12 control individuals) were enrolled. Participants underwent full-brain functional magnetic resonance imaging. Main Outcome Measure(s): Functional data were acquired using blood oxygen level–dependent (BOLD) echoplanar imaging. Independent t tests were conducted to identify between-groups differences in BOLD signal changes during all images of the PIT. Paired t tests were computed to examine differences in BOLD signal change between sport-specific and ADL images in the ACLR group. Results: Increased activation in the inferior parietal lobule and the mediodorsal thalamus was observed during PIT in the ACLR group. An inability to suppress the default mode network in the ACLR group was noted. The ACLR group exhibited increased activation in the cerebellum and inferior occipital regions during the sport-specific images versus the ADL images, but no other regions of interest demonstrated differences. Conclusion: After ACLR, patients may be more predisposed to fear, anxiety, and pain during sport-specific activities and ADLs. Psychosocial interventions may be warranted after ACLR to reduce injury-related fear and mitigate potentially maladaptive neuroplasticity. pubtype: Academic Journal doctype: diagnostic images research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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