Open and Closed Endotracheal Suction Systems Divergently Affect Pulmonary Function in Mechanically Ventilated Subjects.

BACKGROUND: In mechanically ventilated subjects, intra-tracheal secretions can be aspirated with either open suction systems (OSS) or closed suction systems (CSS). In contrast to CSS, conventional OSS require temporarily disconnecting the patient from the ventilator, which briefly diminishes PEEP an...

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Publicado en:Respiratory Care Vol. 66; no. 5; pp. 785 - 793
Autores principales: Raimundo, Rodrigo Daminello, Sato, Monica Akemi, da Silva, Talita Dias, de Abreu, Luiz Carlos, Valenti, Vitor Engracia, Riggs, Daniel William, Carll, Alex Perrow
Formato: research tables/charts randomized controlled trial Journal Article
Publicado: Mary Ann Liebert, Inc. May2021
Acceso en línea:Ver este registro en EBSCOhost
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      dt: May2021
      vid: 66
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      pub: Mary Ann Liebert, Inc.
      place: New Rochelle, New York
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        atl: Open and Closed Endotracheal Suction Systems Divergently Affect Pulmonary Function in Mechanically Ventilated Subjects.
      aug:
        au:
          Raimundo, Rodrigo Daminello
          Sato, Monica Akemi
          da Silva, Talita Dias
          de Abreu, Luiz Carlos
          Valenti, Vitor Engracia
          Riggs, Daniel William
          Carll, Alex Perrow
        affil: Laboratório de delineamento de estudos e escrita científica, Faculdade de Medicina do ABC, Santo Andre, Sao Paulo, Brazil
      sug:
        subj:
          Suctioning, Endotracheal Methods
          Suctioning, Endotracheal Adverse Effects
          Lung Physiopathology
          Cardiopulmonary Physiology Evaluation
          Respiration, Artificial
          Ventilator Patients
          Human
          Intensive Care Units
          Quasi-Experimental Studies
          Crossover Design
          Randomized Controlled Trials
          Airway Resistance
          Heart Rate
          Arterial Pressure
          Aspiration
          Regression
          Lung Injury Prevention and Control
          Lung Injury Etiology
          Middle Age
          Male
          Female
          Descriptive Statistics
          Middle Aged: 45-64 years
          Male
          Female
      ab: BACKGROUND: In mechanically ventilated subjects, intra-tracheal secretions can be aspirated with either open suction systems (OSS) or closed suction systems (CSS). In contrast to CSS, conventional OSS require temporarily disconnecting the patient from the ventilator, which briefly diminishes PEEP and oxygen supply. On the other hand, CSS are more expensive and less effective at aspirating secretions. Thus, it was hypothesized that the 2 procedures differentially affect pulmonary and cardiovascular parameters after suction. METHODS: Subjects in the ICU (N = 66) were quasi-randomized for initial treatment with OSS or CSS in a crossover design. To compare the potential for these suction systems to compromise cardiorespiratory stability, changes in cardiopulmonary physiology were assessed from before to just after use of each suction system (three 10-s aspirations). RESULTS: For most pulmonary and cardiovascular parameters (ie, peak inspiratory pressure, airway resistance, pressure plateau, heart rate, and arterial pressures), the effects of aspiration inversely correlated with baseline values for that parameter, with a similar regression slope between suction systems. However, when controlling for baseline values, OSS caused significantly greater increases in airway resistance and peak inspiratory pressure (P < .001 and < .01 vs CSS, respectively). CONCLUSIONS: Elevated airway resistance prior to endotracheal suction may justify use of a CSS and contraindicate a conventional OSS in mechanically ventilated subjects. Adoption of this approach into clinical guidelines may prevent suction-induced pulmonary injury in subjects, especially for those with underlying diseases involving increased airway resistance or increased alveolar pressure. (ClinicalTrials.gov registration: NCT03256214.)
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        randomized controlled trial
        Journal Article
      ougenre: Article
    language: English
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